ANEMIA STATUS OF CHRONIC HEPATITIS B PATIENTS TREATED WITH NUCLEOTIDE ANALOG THERAPY AT HAI PHONG INTERNATIONAL GENERAL HOSPITAL IN 2020

Nguyễn Thị Thu Phương1,2,, Trần Thị Ngân1,2
1 Haiphong University of Medicine and Pharmacy
2 Hai Phong International General Hospital

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Abstract

Chronic hepatitis B virus infection is a serious global health problem. Anemia is the most common complication of cirrhosis and occurs in 75% of cases. The etiology of anemia in liver disease is diverse. Therefore, we carried out this study with the aim of investigating anemia in chronic hepatitis B patients treated at Hai Phong International General Hospital in 2020. Our study shows the rate Anemia in 2026 chronic hepatitis B patients after 12 weeks of treatment was 9.1% with an average hemoglobin concentration of 119,3 ± 13,7 g/dL. The results of multivariable logistic regression analysis showed that weight, number of comorbidities and cirrhosis significantly affected the occurrence of anemia in the study group with the odds ratio (Odd ratio) respectively: 0,97, 1,25, 2,07 (p < 0,05). This result contributes to supporting clinicians in the prognostication and monitoring of hepatitis B patients to improve treatment effectiveness.

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References

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