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Date Published: 13/03/2022
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DOI: https://doi.org/10.51298/vmj.v510i2.1984
Issue
Vol. 510 No. 2 (2022)
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Duy Đông, N. ., Văn Sơn, N. ., Bá Nghĩa, P. ., & Văn Duy, T. . (2022). PROGNOSTIC VALUE OF NEUTROPHIL-LYMPHOCYTE RATIO IN MODERATELY AND SEVERELY COVID-19 PATIENTS TREATED AT INFECTIOUS FIELD HOSPITAL NO.5G. Vietnam Medical Journal, 510(2). https://doi.org/10.51298/vmj.v510i2.1984

PROGNOSTIC VALUE OF NEUTROPHIL-LYMPHOCYTE RATIO IN MODERATELY AND SEVERELY COVID-19 PATIENTS TREATED AT INFECTIOUS FIELD HOSPITAL NO.5G

Nguyễn Duy Đông1,, Nguyễn Văn Sơn1, Phan Bá Nghĩa1, Trần Văn Duy1
1 Military Hospital 103

Main Article Content

Abstract

Objective: To evaluate the prognostic value of the neutrophil-lymphocyte ratio (NLR) in moderately and severely COVID-19 patients. Methods: This is a prospective study conducted at the Infectious Field Hospital No.5G. All moderately and severely Covid-19 patients were included in the study between September 6, 2021 and October 30, 2021. We collected age, gender, and NLR information from the first complete blood count at admission. We divided patients into two groups: patients under 60 and patients over 60 years old. We chose the best NLR cut-off value based on Youden index and receiver operating characteristic (ROC) curve analysis and the target endpoint was mortality or survive. Results: The study showed that 342 patients were treated in the critical patient department, 54 patients (15.8%) died. When we assessed the correlation between NLR and mortality of all patients, regardless of their age, the AUC was 0.781 (95% CI: 0.71-0.85; p < 0.0001). The Youden index indicates that the best cut-off value of NLR was > 14.2 with a sensitivity of 70.4% and a specificity of 77.8%. When patient age ≥ 60 and NLR ≥ 11.25 it showed 75.0% sensitivity and 68.2% specificity for predicting mortality. When NLR ≥ 13.15 and patient age < 60, sensitivity and specificity were 90.0% and 76.9%, respectively. Conclusion: NLR has been shown to have high specificity and sensitivity in helping to identify patients who need more intensive care in moderately and severely COVID-19 patients.

Article Details

Keywords

COVID-19, neutrophil-lymphocyte ratio, prognosis

References

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