CLINICOPATHOLOGICAL CHARACTERISTICS AND SURGICAL TREATMENT OUTCOMES OF PATIENT WITH PHYLLODES TUMOR AT VIETNAM NATIONAL CANCER HOSPITAL
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Abstract
Objectives:To study clinicopathological characteristics and surgical treatment outcomes of phyllodes tumor patients. Patients and methods: A descriptive study was conducted with 53 phyllodes tumor patients who underwent operation Jan 2016 to Jan 2018 at Vietnam National Cancer hospital. Results: Mean age was 41,2 ± 8,5, popular in age range 41 -60 at 43,4%. Mean size of tumor was 8,94 ± 4,15cm (3- 25cm); the prevalence of axillary lymph nodes found by clinical examination was 33,9%. 70,7% of cases were evaluated at TIRADS 3 on mamography. Percentages of patients according to histological classificcation as benign, borderline, and malignant respectively were 66%, 18,9%, 15,1%. Percentages of patients according to surgical indications: wide excision 66,1%, simple mastectomy 24,5%, mastectomy combining with axillary lymph node dissection 9,4%. Prevalence of recurrence was 15,1%. Percentage of recurrence in benign, boderline and malignant phyllodes patients respectively were: 8,6%; 20% and 37,5%. Mean time from treatment to recurrence was 22.5 months.
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Keywords
Phyllodes tumor, Breast surgery, Recurrent phyllodes tumor
References
2. World Health Organization. Histological typing of breast tumors. Tumori 1982;68:181–98.
3. Zhang Y, Kleer CG. Phyllodes tumor of the breast: histopathologic features, differential diagnosis, and molecular/genetic updates. Arch Pathol Lab Med. 2016;140:665-71.
4. Võ Đăng Hùng (2013). Nghiên cứu chẩn đoán – điều trị bướu diệp thể vú, luận án tiến sĩ, Đại học Y dược TP Hồ Chí Minh.
5. Gianluca Spitaleri, Antonio Toesca, Edoardo Botteri, et al. (2013). Breast phyllodes tumor: a review of literature and a single center retrospective series analysis. Critical reviews in oncology/hematology, 88 (2), 427-436.
6. Jose M Pimiento, Pranjali V Gadgil, Alfredo A Santillan, et al. (2011). Phyllodes tumors: race-related differences. Journal of the American College of Surgeons, 213 (4), 537-542.
7. Mengsu Xiao, Qingli Zhu, Yuxin Jiang, et al. (2015). Local recurrent phyllodes tumors of the breast: clinical and sonographic features. Journal of Ultrasound in Medicine, 34 (9), 1631-1638.