KHẢO SÁT TỶ LỆ KHÁNG KHÁNG SINH CỦA VI KHUẨN ESCHERICHIA COLI GÂY NHIỄM KHUẨN TIẾT NIỆU Ở BỆNH NHÂN ĐÁI THÁO ĐƯỜNG

Abstract

Urinary tract infections are more common, more severe, and have a worse outcome in patients with type 2 diabetes. They are mainly caused by bacteria, especially E. coli. Objective: to investigate the rate of E. coli causing urinary tract infections in diabetic patients and the resistance level of isolated E. coli. Methods: a cross-sectional descriptive study, among 295 patients were diagnosed with diabetes and had a urine culture, at the Department of Endocrinology, Nghe An General Freindship Hospital from 01/2021 – 04/2021. Results: The rate of isolated E. coli causing urinary tract infections accounted for 65.3% (17/26) of the total bacterial strains. The percentage of ESBL seminarians was 47.4%. E.coli is resistant to the Quinolone group of antibiotics from 42.1 to 57.9%. Resistance to Cephalosporin group 42.1–73.7%; Ampicillin and Piperacilli 84.2%; Cotrimoxazol and Ampicillin/Sulbactam were 57.9%. However, the antibiotics of the Carbapenem, Fosmicin and Amikacin groups are still sensitive to E.coli bacteria with the rate > 95% -100%. Conclusion: E. coli is the leading cause of urinary tract infections in diabetic patients and is resistant to all antibiotics to varying degrees. Therefore, regular monitoring of the level of antibiotic resistance of bacteria helps to control infection, manage and use antibiotics effectively.