SỰ PHÂN BỐ VÀ TÍNH KHÁNG THUỐC CỦA TRỰC KHUẨN MỦ XANH TẠI BỆNH VIỆN ĐA KHOA TỈNH THANH HÓA NĂM 2020

Abstract

Pseudomonas aeruginosa is an opportunistic pathogen that causes most chronic infections in humans. Purposes: This study was performed to determine the infection rate and antibiotic resistance characteristics of pseudomonas aeruginosa from the clinical specimens. Subjects and methods: Cross-sectional description was performed at Thanh Hoa General Hospital from January to August 2020. Pseudomonas aeruginosa is isolated from a number of different specimens at the Department of Microbiology Isolation, identification and determination of antibiotic sensitivity. Results: 78 strains of Pseudomonas aeruginosa. Isolated mainly from urine, pus, wound fluid, sputum, tracheal suction fluid and blood. That of 55,8% resistant to Ceftazidime, 53,3% resistant to Cefepime, 24,3% resistant to Piperacillin/Tazobactam. Many previous studies showed that antibiotics such as Imipenem, Meropenem, Ciprofloxacin, Gentamicin, Amikacin and Tobramycin had been thought to be good options, but in this study those which increased in resistance to antibiotics immensely. Previously, Pseudomonas aeruginosa was completely sensitive to Colistin but now the resistance 8,3%. Conclusion: Keeping continuously of monitoring to the antibiotic sensitivity of Pseudomonas aeruginosa is essential and reasonable and a need for being prescribed properly by the clinician to limit the spread of antibiotic resistance.