RESEARCH ON THE RELATIONSHIP BETWEEN ARTERIAL STIFFNESS BY PULSE WAVE VELOCITY WITH SOME RISK FACTORS IN PATIENTS WITH CHRONIC ISCHEMIC HEART DISEASE

Hồ Thị Kim Ngân1, Nguyễn Đình Linh1, Trần Đức Hùng2,
1 Vietnam Military Medical University
2 Military Hospital 103

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Abstract

Objectives: To find out the relationship between arterial stiffness by pulse wave velocity with some risk factors in patients with chronic ischemic heart disease (CIHD). Subjects and methods: The patient group included 61 patients with chronic ischemic heart disease (defined as angiographic percent diameter stenosis ≥ 50%). The control group included 31 patients had normal coronary angiography. Results: The average age of the control group and the CIHD group was 68,26 ± 6,66 and 70,10 ± 7,15 years, respectively. The male in CIHD group was 60,7%, higher than the female group (39.3%). The mean PWV of CIHD group (15.66 ± 1.88 m/s) was higher than control group (13.35 ± 1.99 m/s). The incidence of elevated PWV (≥ 14 m/s) in the patient group (85.2%) was significantly higher than control group (38.7%). Increased PWV was associated with CIHD with OR = 9,148 (95% CI: 3,327 – 25,153). PWV in hypertensive patients of  CIHD and control groups were: 15.75 ± 1.99 and 13.8 ± 1.83 m/s, respectively; in patients with diabetes mellitus (DM): 15.89 ± 2.07 and 14.06 ± 1.29 m/s; smokers: 15.76 ± 1.97 and 13.82 ± 1.45 m/s; overweight people: 15.69 ± 1.79 and 13.59 ± 2.12 m/s. Conclusion: The mean PWV of CIHD group was higher than control group. The incidence of elevated PWV (≥ 14 m/s) in CIHD was more than control group. In patients with hypertension, diabetes, smoking, overweight, the PWV of the CIHD group was significantly higher than that of the control group, p < 0.05.

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References

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