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Date Published: 15/04/2022
Abstract Views: 298
Views PDF: 217
DOI: https://doi.org/10.51298/vmj.v511i1.2073
Issue
Vol. 511 No. 1 (2022)
Section
Các bài báo
How to Cite
Thị Hương Trà, T. ., Ngọc Đông, P. ., & Thị Minh Tuệ, Đặng . (2022). CHARACTERISTICS OF DRY EYE IN PATIENTS WITH PRIMARY SJÖGREN SYNDROME. Vietnam Medical Journal, 511(1). https://doi.org/10.51298/vmj.v511i1.2073

CHARACTERISTICS OF DRY EYE IN PATIENTS WITH PRIMARY SJÖGREN SYNDROME

Trần Thị Hương Trà1,, Phạm Ngọc Đông1,2, Đặng Thị Minh Tuệ1
1 Central Eye Hospital
2 University of Medicine and Pharmacy, Vietnam National University, Hanoi

Main Article Content

Abstract

Purpose: Describe the charecteristics of dry eye in patients with primary Sjögren Syndrome (pSS). Patients and method:  Prospective study carried on 40 eyes of 20 patients with primary SS. Collected and analized indicators were ages, sex, VA, OSDI lacrimation (TBUT, Shirmer I), corneal staining score, conjuntival staining score, systemic symtoms. Result: The results showed that: the average age of the patients is 51.5±10.4, female-to-male ratio is of 9/1. Common systemic symtoms: xerostomia, fatigue, colpoxerosis, swelling of the parotid glands. The average score of OSDI, Schirmer I, TBUT, corneal staining score and conjunctival staining score are: 64.7±14.03, 3.23±3.18, 0.7±1.16s, 12.5±2.41, 10.28±3.42, respectively. Conclusion: Sjögren symtom Dry eye (SSDE) is more common in women, with more severe symtoms than non Sjögren symtom Dry eye (NSDE).

Article Details

Keywords

Dry eye, Sjögren Syndrome

References

1. Craig JP, Nichols KK, Akpek EK, al e. TFOS DEWS II Definition and Classification Report. The ocular surface 2017;15(3):276-283.
2. Stapleton F, Alves M, Bunya VY, et al. TFOS DEWS II Epidemiology Report. Ocul Surf. 2017;15(3):334-365.
3. Qin B, Wang J, Yang Z, et al. Epidemiology of primary Sjögren's syndrome: a systematic review and meta-analysis. Ann Rheum Dis. 2015;74(11):1983-1989.
4. Nguyễn Tiến Đạt. Đánh giá hiệu quả của Diquafosol sodium 3% trong điều trị khô mắt vừa và nặng. Luận văn thạc sĩ y học, Nhãn khoa, Đại học Y Hà Nội. 2017.
5. Vitale S, Goodman LA, Reed GF, Smith JA. Comparison of the NEI-VFQ and OSDI questionnaires in patients with Sjögren's syndrome-related dry eye. Health and Quality of Life Outcomes. 2004;2(1):44.
6. D Xu, S Zhao, Q Li3, al e. Characteristics of Chinese patients with primary Sjogren’s syndrome: preliminary report of a multi-centre registration study. Lupus. 2020;29:45-51.
7. Cubuk MO, Ucgul AY, Ozgur A, Ozulken K, Yuksel E. Topical cyclosporine a (0.05%) treatment in dry eye patients: a comparison study of Sjogren's syndrome versus non-Sjogren's syndrome. Int Ophthalmol. 2021;41(4):1479-1485.
8. Kang M-J, Kim Y-H, Chou M, et al. Evaluation of the Efficacy and Safety of A Novel 0.05% Cyclosporin A Topical Nanoemulsion in Primary Sjögren’s Syndrome Dry Eye. Ocular Immunology and Inflammation. 2020;28(3):370-378.