Article Sidebar

PDF
Date Published: 15/04/2022
Abstract Views: 144
Views PDF: 109
DOI: https://doi.org/10.51298/vmj.v511i1.2088
Issue
Vol. 511 No. 1 (2022)
Section
Các bài báo
How to Cite
Văn Hữu, P. ., Quang Tuyển, B. ., Văn Hệ, Đồng ., & Thành Bắc, N. . (2022). EVALUATE THE RESULTS OF TREATMENT ON MALIGNANT GLIOMA AND INFLUENCING FACTORS. Vietnam Medical Journal, 511(1). https://doi.org/10.51298/vmj.v511i1.2088

EVALUATE THE RESULTS OF TREATMENT ON MALIGNANT GLIOMA AND INFLUENCING FACTORS

Phạm Văn Hữu1,, Bùi Quang Tuyển2, Đồng Văn Hệ3, Nguyễn Thành Bắc2
1 Thai Binh General Hospital
2 Military Hospital 103, Vietnam Military Medical University
3 Departement of Neurosurgery, Vietnam-Germany Friendship Hospital

Main Article Content

Abstract

Aim: evaluate the results of treatment on malignant glioma and influencing factors. Object and method: a prospective, descriptive research on 77 patients were detected with malignant gliomas and underwent microneurosurgery in Neurosurgery Center of Viet Duc University Hospital between July 2015 and June 2017. Result: clinical symptom includes: increased intracranial pressure syndrome 88.3%, paralysis 40.3%, epilepsy 16.9%. Complication: Bleeding 6.5%, edema 6.5%, CSF leakage 1.3%. Extent of tumor removal: Gross total resection 55.8%, subtotal resection 31.2%. Result: good 71.4%, medium 14.3% and poor 14.3%. The survival averaging 16.94 months. Conclusion: microsurgery and neuronavigation enable to remove tumor better. The extent of tumor removal, chemo-radiotherapy help lengthen the survival time after surgery.

Article Details

Keywords

gliomas, microsurgery, chemo-radiotherapy

References

1. Friedman, H.S., T. Kerby, and H. Calvert, Temozolomide and treatment of malignant glioma. Clin Cancer Res, 2000. 6(7): p. 2585-97.
2. Nayak, L. and D.A. Reardon, High-grade Gliomas. Continuum (Minneap Minn), 2017. 23(6, Neuro-oncology): p. 1548-1563.
3. Forsyth, P.A. and J.B. Posner, Headaches in patients with brain tumors: a study of 111 patients. Neurology, 1993. 43(9): p. 1678-83.
4. Bordey, A. and H. Sontheimer, Properties of human glial cells associated with epileptic seizure foci. Epilepsy Res, 1998. 32(1-2): p. 286-303.
5. Jackson, C., M. Westphal, and A. Quiñones-Hinojosa, Complications of glioma surgery. Handb Clin Neurol, 2016. 134: p. 201-18.
6. Verburg, N. and P.C. de Witt Hamer, State-of-the-art imaging for glioma surgery. Neurosurg Rev, 2021. 44(3): p. 1331-1343.
7. Yaşargil, M.G., P.A. Kadri, and D.C. Yasargil, Microsurgery for malignant gliomas. J Neurooncol, 2004. 69(1-3): p. 67-81.
8. Orringer, D., et al., Extent of resection in patients with glioblastoma: limiting factors, perception of resectability, and effect on survival. J Neurosurg, 2012. 117(5): p. 851-9.
9. Manrique-Guzman S, H.P.T. and R.p. F., Glioblastoma, in Surgical Management of Glioblastoma, S. Manrique-Guzman, Editor. 2017: Neurological Center, Neurosurgery Department, Mexico City, Mexico. p. 243-261