Article Sidebar
Views PDF: 730
EVALUATION OF ANTIBIOTIC USE IN PATIENTS WITH HOSPITAL ACQUIRED PNEUMONIAE AND VENTILATOR-ASSOCIATED PNEUMONIA IN TUYEN QUANG GENERAL HOSPITAL
Main Article Content
Abstract
Objectives: To evaluate the appropriateness of empirical antimicrobial therapy, antimicrobials dosing and administration in hospital-acquired pneumoniae (HAP) and ventilator-associated pneumoniae (VAP) in Tuyen Quang General Hospital. Subjects and methods: Patients who were diagnosed with HAP/VAP from 1/2019 to 9/2020. A retrospective descriptive study. Results: Totally 121 patients were included in the study; the average age was 63.8 ± 18.1 years; the average length of antibiotic therapy (LOT) was 17.6 ± 6.5 days; the proportion of microbiological culture with positive bacterial result was 37.9%; thepredominantpathogens were Acninetobacter baumannii (18/55); Pseudomonas aeruginosa (16/55); the appropriateness rate of empirical antibiotic therapy, dosing and drug administrationwas 43.0%; 26.4%; 100%, respectively; the rate of clinical response was 50.4%. Conclusion: The study has shown several outstanding characteristics of antibiotic use in patients with HAP/VAP. The research results will be an important basis for the hospital to implement several specific strategies to improve the effectiveness of antimicrobials in treating these infections.
Article Details
Keywords
Hospital-acquired pneumoniae, ventilator-associated pneumoniae, antimicrobials therapy
References
2. IDSA/ATS (2005), "Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia", Am J Respir Crit Care Med, 171(4), pp. 388-416.
3. Kalil A. C., Metersky M. L., et al. (2016), "Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the IIDS and the ATS", Clin Infect Dis, 63(5), pp. e61-e111.
4. Torres A., Niederman M. S., et al. (2017), "International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia: Guidelines for the management of hospital-acquired pneumonia (HAP)/ventilator-associated pneumonia (VAP)", Eur Respir J, 50(3).