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EVALUATION OF ANTIBIOTIC USE IN PATIENTS WITH HOSPITAL ACQUIRED PNEUMONIAE AND VENTILATOR-ASSOCIATED PNEUMONIA IN TUYEN QUANG GENERAL HOSPITAL
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Abstract
Objectives: To evaluate the appropriateness of empirical antimicrobial therapy, antimicrobials dosing and administration in hospital-acquired pneumoniae (HAP) and ventilator-associated pneumoniae (VAP) in Tuyen Quang General Hospital. Subjects and methods: Patients who were diagnosed with HAP/VAP from 1/2019 to 9/2020. A retrospective descriptive study. Results: Totally 121 patients were included in the study; the average age was 63.8 ± 18.1 years; the average length of antibiotic therapy (LOT) was 17.6 ± 6.5 days; the proportion of microbiological culture with positive bacterial result was 37.9%; thepredominantpathogens were Acninetobacter baumannii (18/55); Pseudomonas aeruginosa (16/55); the appropriateness rate of empirical antibiotic therapy, dosing and drug administrationwas 43.0%; 26.4%; 100%, respectively; the rate of clinical response was 50.4%. Conclusion: The study has shown several outstanding characteristics of antibiotic use in patients with HAP/VAP. The research results will be an important basis for the hospital to implement several specific strategies to improve the effectiveness of antimicrobials in treating these infections.
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Keywords
Hospital-acquired pneumoniae, ventilator-associated pneumoniae, antimicrobials therapy
References
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