CLINICAL CHARACTERISTICS OF MULTIPLESSCLEROSIS PATIENTS, TREATED AT DEPARTMENT OF NEUROLOGY, BACH MAI HOSPITAL FROM 1/2018-7/2020

Lê Thị Vân1,, Trương Tuấn Anh1
1 Nam Dinh University of Nursing

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Abstract

Objectives: To describe clinical characteristics of patients with multiple sclerosis, treated at the neurology department, Bach Mai hospital from 1/2018-7/2020. Methods: A retrospective study was performed on 71 patients with multiple sclerosis. Results: There were 54 female patients with multiple sclerosis, female/male ratio ≈ 3:1. The average age of the disease was 41.9 ± 13.6 years old, usually under 40 years old. Common symptoms are optic nerve damage, motor paralysis due to spinal cord injury alone, and sensory disturbances. The majority (81.69%) of patients recovered after the first episode, lasting from 1 to 6 months. Neuromyelitis optica – NMOwas seen with the highest rate (39.44% of the patients). Conclusion: Patients with multiple sclerosis have diverse clinical symptoms, mainly lesions causing motor paralysis and sensory disturbances. Despite the high rate of recovery after the first episode, the patient's quality of life is severely affected by multi-phenotypic, multi-site lesions.

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References

1. Lê Văn Thính, Nguyễn Văn Tuận. Nghiên cứu đặc điểm lâm sàng và cận lâm sàng bệnh xơ cứng rải rác của hệ thần kinh trung ương Y học lâm sàng bệnh viện Bạch Mai. 2006;10:87 - 90.
2. Trojano M, Lucchese G, Graziano G, et al. Geographical variations in sex ratio trends over time in multiple sclerosis. PLoS One. 2012;7(10): e48078.
3. Simone IL, Carrara D, Tortorella C, et al. Course and prognosis in early-onset MS: comparison with adult-onset forms. Neurology. 2002;59(12):1922-1928.
4. Duquette P, Murray TJ, Pleines J, et al. Multiple sclerosis in childhood: clinical profile in 125 patients. J Pediatr. 1987;111(3):359-363.
5. Olsson T, Barcellos LF, Alfredsson LJNRN. Interactions between genetic, lifestyle and environmental risk factors for multiple sclerosis. 2017;13(1):25.
6. Tremlett H, Van Der Mei IA, Pittas F, et al. Monthly ambient sunlight, infections and relapse rates in multiple sclerosis. 2008;31(4):271-279.
7. Beck RW, Chandler DL, Cole SR, et al. Interferon beta-1a for early multiple sclerosis: CHAMPS trial subgroup analyses. Ann Neurol. 2002;51(4):481-490.
8. Nociti V, Cianfoni A, Mirabella M, et al. Clinical characteristics, course and prognosis of spinal multiple sclerosis. Spinal Cord. 2005;43(12):731-734.