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Date Published: 21/04/2022
Abstract Views: 551
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DOI: https://doi.org/10.51298/vmj.v511i2.2142
Issue
Vol. 511 No. 2 (2022)
Section
Các bài báo
How to Cite
Ngọc Trung Dung, H. ., Kim Ngọc, T. ., Phú Nguyên Thảo, L. ., Thị Ngọc Tuyết, N. ., & Công Luận, T. . (2022). EVALUATE TOXICITY AND HEPATOPROTECTIVE EFFECTS OF TWO PRODUCTS CONTAINING CORDYCEPS MILITARIS OF LAVITE Co., Ltd. Vietnam Medical Journal, 511(2). https://doi.org/10.51298/vmj.v511i2.2142

EVALUATE TOXICITY AND HEPATOPROTECTIVE EFFECTS OF TWO PRODUCTS CONTAINING CORDYCEPS MILITARIS OF LAVITE Co., Ltd.

Huỳnh Ngọc Trung Dung1, Trì Kim Ngọc1, Lê Phú Nguyên Thảo1, Nguyễn Thị Ngọc Tuyết2, Trần Công Luận1,
1 Nursing Pharmaceutical Sciences, Tay Do University
2 Lavite Co., Ltd

Main Article Content

Abstract

Introduction: Cordyceps militaris is widely used in treatment and improving human health such as: Anti-cancer, immunomodulatory, antioxidant. Methods: To evaluate the irregular toxicity and hepatoprotective effects of Cordyceps-containing products manufactured by Lavite Co., Ltd., the study was conducted through the abnormal oral toxicity test on rat. Hepatoprotective effects on a long-term ethanol-induced rat liver injury model. Results: Both samples of The aqueous extract of Cordyceps Hector Ginseng (11.76-23.52 mL/kg of mouse weight/day equivalent to a dose of 50-100 mL/day) and Capsules 100% Hector Cordyceps (58.8-117.6 mg powder/kg body weight equivalent to dose 1-2 tablets/day) had no abnormal toxicity in test rats and had hepatoprotective effects, decreased plasma AST-ALT liver enzyme activity and decreased MDA content inhibiting hepatocyte lipid peroxidation in rat liver. Conclusion: Both samples can be used as a safe preparation with a hepatoprotective effect.

Article Details

Keywords

Cordyceps militaris, hepatoprotective effects, irregular toxicity

References

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