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Date Published: 25/04/2022
Abstract Views: 147
Views PDF: 143
DOI: https://doi.org/10.51298/vmj.v512i1.2190
Issue
Vol. 512 No. 1 (2022)
Section
Các bài báo
How to Cite
Văn Hùng, P. ., Hữu Thiên, Đoàn ., Hồng Trâm, T. ., & Huy Bình, N. . (2022). THE RELATIONSHIP BETWEEN C-PEPTIDE CONCENTRATION AND MICROVASCULAR COMPLICATIONS OF TYPE 2 DIABETES PATIENTS AT HANOI MEDICAL UNIVERSITY HOSPITAL. Vietnam Medical Journal, 512(1). https://doi.org/10.51298/vmj.v512i1.2190

THE RELATIONSHIP BETWEEN C-PEPTIDE CONCENTRATION AND MICROVASCULAR COMPLICATIONS OF TYPE 2 DIABETES PATIENTS AT HANOI MEDICAL UNIVERSITY HOSPITAL

Phạm Văn Hùng1,, Đoàn Hữu Thiên1, Trần Hồng Trâm1, Nguyễn Huy Bình2
1 National Institute For Control of Vaccine and Biologicals, Ministry of Health
2 Hanoi Medical University

Main Article Content

Abstract

Objective: To determine the relationship between C-peptide concentration and microvascular complications of type 2 diabetes patients at Hanoi Medical University Hospital in 2021. Subjects: 96 patients with type 2 diabetes who came for a health check-up at the Medical Examination Department of Hanoi Medical University Hospital. Methods: Cross sectional description. Results and conclusions: The average fasting C - Peptide concentration was 0.84 ± 0.37 nmol/l. Low C-peptide levels are associated with the occurrence of microalbuminuria and retinal damage in diabetic patients.

Article Details

Keywords

C-Peptide, diabetic retinopathy, microalbuminuria

References

1. Gross JL, de Azevedo MJ, Silveiro SP, Canani LH, Caramori ML, Zelmanovitz T. (2005) Diabetic nephropathy: diagnosis, prevention, and treatment. Diabetes Care. 2005;28(1):164-176. doi:10.2337/diacare.28.1.164
2. Ahmad T, Ulhaq I, Mawani M, Islam N. (2017) Microalbuminuria in Type-2 Diabetes Mellitus; the tip of iceberg of diabetic complications. Pak J Med Sci. 2017;33(3):519-523. doi:10.12669/ pjms.333.12537
3. Yau JWY, Rogers SL, Kawasaki R, et al. (2012) Global prevalence and major risk factors of diabetic retinopathy. Diabetes Care. 2012;35(3):556-564. doi:10.2337/dc11-1909
4. Chowta MN, Adhikari PM, Chowta NK, Shenoy AK, D’Souza S. (2010) Serum C peptide level and renal function in diabetes mellitus. Indian J Nephrol. 2010;20(1):25-28. doi:10.4103/0971-4065.62093
5. Masoom MM, Albiladi F. (2017) C-Peptide as a Marker for Diabetic Nephropathy. Intern Med Open Access. 2017; 07(03). doi:10.4172/2165-8048. 1000245
6. Bo S, Cavallo-Perin P, Gentile L, Repetti E, Pagano G. (2000) Relationship of residual beta-cell function, metabolic control and chronic complications in type 2 diabetes mellitus. Acta Diabetol. 2000;37(3):125-129. doi: 10.1007/ s005920070014
7. Sjöquist M, Huang W, Johansson BL. (1998) Effects of C-peptide on renal function at the early stage of experimental diabetes. Kidney Int. 1998; 54(3): 758-764. doi:10.1046/j.1523-1755. 1998.00074.x
8. Trần Mai Nguyên, Đỗ Trung Quân (2021) Khảo sát nồng độ C – peptide và mối liên quan với biến chứng vi mạch ở bệnh nhân đái tháo đường type 2. Tạp chí Y học Việt Nam. Tập 509, tháng 9 số 1. tr.85-88.