INVESTIGATION SOME CLINICAL, PARACLINICAL AND BLOOD LACTATE CHARACTERISTICS IN PATIENTS WITH ACUTE HEART FAILURE WITH REDUCED EJECTION FRACTION WITHOUT CARDIOGENIC SHOCK

Nguyễn Hữu Việt1,, Đinh Đức Lộc2, Bùi Long1,3, Đỗ Doãn Lợi3
1 Friendship Hospital
2 Thai Nguyen University of Medicine and Pharmacy
3 Hanoi Medical University

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Abstract

Objectives: To describe some clinical, paraclinical and blood lactate levels in patients with acute heart failure with reduced ejection fraction without cardiogenic shock.Study subjects: Patients diagnosed with acute heart failure with reduced ejection fraction without cardiogenic shock were treated at the Cardiology Institute, Bach Mai Hospital from May 2020 to June 2021. Research Methods: Cross-sectional descriptive. Results and conclusions: The average age of 88 study patients was 64,57 ± 14,42 years, 70,5% were male. The cause of heart failure due to coronary artery disease accounted for 62,5%, followed by hypertension (15,9%), cardiomyopathy (11,4%) and valvular heart disease (10,4%). The rate of new-onset heart failure accounted for 13,0%. Clinical features: SBP 126,4 ± 18,55 mmHg, SBP 80,68 ± 12,80 mmHg; heart rate mean 98,57 ± 16,31 beats/min; respiratory rate average 26,80 ± 4,31 times/min; SpO2 TB 92,06 ± 2,41 %; 100% of patients have wet rales; 98,9% dyspnea NYHA III, IV; 30,7% edema of the lower extremities; 29,5% hepatomegaly and 21,6% atrial fibrillation. Paraclinical characteristics: mean ejection fraction EF 27,89 ± 5,81%; average concentration of NT - proBNP 824,13 [377,30; 4138,0] pmol/L; the mean troponin T concentration was 39,81 [6,80; 130,0] ng/L; mean glomerular filtration rate 47,16 ± 20,39 ml/min, average blood lactate concentration 1,80 ± 0,71 mmol/l.

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References

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