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FACTORS AFFECTING HEIGHT VELOCITY RESPONSE IN rhGH- TREATED CHILDREN WITH GROWTH HORMONE DEFICIENCY
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Abstract
Growth hormone deficiency is a condition that occurs when the pituitary gland does not produce enough growth hormone. This is the most common endocrine cause in short status which incidence is between 1/3500 – 1/4000. Objective: to study factors affecting the height velocity response in rhGH- treated children with growth hormone deficiency. Patiens and Method: A case series study and comparing before and after treatment with rhGH, 159 patients with growth hormone deficiency was evaluated at National Children’s Hospital from 1/2010 to 6/2019. Results: A significantly negative correlation was seen between first year change in height (cm, SDS) and bone age, chronological age at initiation of treatmen while a significantly negative correlation was seen between first year change in height cm and peak serum GH level.
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Keywords
recombinant growth hormone, growth hormone deficiency, Short stature in Children
References
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