COST – EFFECTIVENESS ANALYSIS OF READY-TO-USE INJECTION PREPARATIONS VERSUS CONVENTIONAL RECONSTITUTED ADMIXTURES: A SYSTEMATIC REVIEW
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Abstract
Backgrounds: Ready-to-use injection preparations are one of the solutions potential to reduce medication errors (ME) related to drugs preparation and administration compared to conventional preparation methods while ensuring the efficacy and safety of drugs. Objectives: To systematically review and assess the health economic evaluations of ready-to-use injection preparations compared to the conventional reconstituted admixtures. Methods: This systematic review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) statement (1). Results: Four eligible studies showed that ready-to-use injection preparations are beneficial in several aspects. They reduced the incidence of ME, thereby reducing ME-related treatment costs, prolonging survival, and improving patients' quality of life. In addition, pre-filled injections may increase the coverage of prophylactic interventions and save more lives. Conclusion: The usage of ready-to-use injections provides both clinical and economic benefits.
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References
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