NHẬN XÉT KẾT QUẢ ĐIỂU TRỊ TRIỆU CHỨNG TRẦM CẢM Ở NGƯỜI BỆNH RỐI LOẠN PHÂN LIỆT CẢM XÚC LOẠI TRẦM CẢM

Abstract

Our study aimed to describe the treatment results of depressive symptoms in patients with schizoaffective disorder, depressive type treated in Institute of Mental Health - Bach Mai hospital. This is a cross-sectional descriptive study including  40 patients diagnosed with schizoaffective disorder depressive type according to ICD-10 diagnostic criteria (F25.1). Results: the mean  age of patients was 30.3±8.2 years. There were more women than men, and the female/male ratio was about 1.4/1. Sertraline was the most common antidepressant used with these patients  (90.0%),the highest  dose was 125 ± 52.8 mg/day. At the start of treatment, 100% of patients had low mood, followed by 87.5% had decreased interest and enjoyment and 82.5 had decreased energy and were easy fatigue. At the end of treatment, all symptoms were relieved. The biggest reduction was found in the symptom of decreased interest and enjoyment, from 87.5% to 22.5%. Common symptoms of depression also showed a dramatic remission before and after treatment. After treatment, the proportion of patients with sleep disorders and poor appetite decreased to about 10% and 20%. Some remaining symptoms such as decreased attention, decreased libido, bleak and pessimistic future accounted for 20%, 20% and 30% respectively. The typical symptoms of depression were still in relative high proportions , such as low mood (57.5%), decreased energy (67.5%), easy fatigue and decreased activity (62.5%), distrust (42.5%).