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Date Published: 02/06/2021
Abstract Views: 398
Views PDF: 251
DOI: https://doi.org/10.51298/vmj.v499i1-2.229
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Vol. 499 No. 1-2 (2021)
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Đức Lam, N., & Văn Hiệp, V. (2021). THE COMPARISON OF THE CIRCULATION EFFECTS AND SIDE EFFECTS OF ONDANSETRON WITH DEXAMETHASONE OR METOCLOPRAMIDE TO PREVENT VOMITING, NAUSEA DURING AND AFTER CESAREAN SECTION. Vietnam Medical Journal, 499(1-2). https://doi.org/10.51298/vmj.v499i1-2.229

THE COMPARISON OF THE CIRCULATION EFFECTS AND SIDE EFFECTS OF ONDANSETRON WITH DEXAMETHASONE OR METOCLOPRAMIDE TO PREVENT VOMITING, NAUSEA DURING AND AFTER CESAREAN SECTION

Nguyễn Đức Lam, Vũ Văn Hiệp

Main Article Content

Abstract

Objective: To compare the effects on circulation and side effects of Ondansetron with Dexamethasone or Metoclopramide to prevent vomiting, nausea during and after cesarean section. Methods: This study was conducted on 90 ASA I-II women (20 - 41 years old) indicated cesarean section with spinal anesthesia, at the Department of Anesthesiology, Hanoi Obstetrics and Gynecology Hospital from January to July 2020. The patients were randomly divided into three similar groups: Group O was administered intravenously 8 mg of Ondansetron, group D with 8mg of Dexamethasone and group M with 10mg of Metoclopramide. The side effects were recorded continuously during surgery and the first 24 hours after surgery. Results: The rate of hypotension in the Ondansetron group was 36.7%; in the Dexamethasone group was 56.7% and in the Metoclopramide group was 53.3%, the difference was statistically significant (p <0.05). The pruritus rates of the three groups were 36.7% ,56.7% and 43.3%, respectively, the difference was not statistically significant (p> 0.05). No cases of epigastric pain, arrhythmia or extrapyramidal syndrome ...


Conclusion: The rate of hypotension in the Ondansetron group was statistically significantly lower than in the Dexamethasone group or the Metoclopramide group with p <0.05. The rates of other side effects such as: pruritus, epigastric pain... did not differ between the three groups. There was no case of arrhythmia or extrapyramidal syndrome.

Article Details

Keywords

Spinal anesthesia, Ondansetrone, Dexamethasone, Metoclopramide, cesarean section

References

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