ĐÁNH GIÁ TÁC DỤNG PHỤ KHI ĐIỀU TRỊ DỰ PHÒNG NÔN, BUỒN NÔN BẰNG DEXAMETHASON 8MG VÀ ONDASETRON 4MG TRONG GÂY TÊ TỦY SỐNG BẰNG BUPIVACAIN VÀ MORPHIN TRONG MỔ LẤY THAI

Abstract

Objective: To evaluate the side effects of postoperative nausea and vomiting prevention by dexamethasone 8mg and ondansetron 4mg in spinal anesthesia with bupivacaine and morphine sulphate for cesarean section performed at Hai Phong Obstetrics Hospital from October 2018 to February 2019. Method: prospective randomized controlled trial interventional study. Control group (group 1): using antiemetics with dexamethasone 8mg, and intervention group (group 2): using a combination of antiemetics with dexamethasone 8mg and ondansetron 4mg. Results: These techniques did not affect to the patients' hemodynamics and respiration. The rate of decreasing mean arterial pressure (MAP) between 20-30% in group 1 (control group) was 3.1%, significantly lower than group 2 (group using 2 drugs) was 8.6%. This rate was lower than in some other studies. Conclusions: We should apply dexamethasone and ondansetron to prevent vomiting, nausea for patients with spinal anesthesia because of being more effective and getting low side effect rate.