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Date Published: 26/04/2022
Abstract Views: 398
Views PDF: 179
DOI: https://doi.org/10.51298/vmj.v512i2.2301
Issue
Vol. 512 No. 2 (2022)
Section
Các bài báo
How to Cite
Thị Kim Phượng, T. ., Phong Thu, L. ., & Hồng Trường, N. . (2022). NEOADJUVANT CHEMOTHERAPY FOR INOPERABLE STAGE III BREAST CANCER PATIENTS TREATED AT ONCOLOGY CENTER OF THAI NGUYEN NATIONAL HOSPITAL. Vietnam Medical Journal, 512(2). https://doi.org/10.51298/vmj.v512i2.2301

NEOADJUVANT CHEMOTHERAPY FOR INOPERABLE STAGE III BREAST CANCER PATIENTS TREATED AT ONCOLOGY CENTER OF THAI NGUYEN NATIONAL HOSPITAL

Trần Thị Kim Phượng1,, Lê Phong Thu1, Nguyễn Hồng Trường1
1 Thai Nguyen University of Medicine and Pharmacy

Main Article Content

Abstract

Purpose: To assess the outcome of neoadjuvant chemotherapy on inoperable stage III breast cancer patients. Study method: cross-sectional study design was conducted on 34 inoperable stage III breast cancer patients treated with neoadjuvant chemotherapy at Oncology Center of Thai Nguyen National Hospital from01/01/2017 to 31/12/2020. Retrospective study was carried out to access the clinical and pathological characteristics of patients as well as the treatment response rate, the rate of changing into operable disease and toxicities. Results: the overall clinical response rate was 67,7%, complete response rate: 11,8%; partial response rate: 55,9%; overall pathological response rate: 16,6%; partial pathological response rate: 79,2%; rate of changing into operable disease was 70,6%, of which 95,8% patients received radical surgery. The toxicities were almost at low grades (1,2). Conclusion: neoadjuvant chemotherapy has the effect on downstaging and changing into inoperable stage on inoperable stage III breast cancer patients. The chemotherapy regiments were tolerable with the low grade of toxicities.

Article Details

Keywords

inoperable stage III breast cancer, locally advanced breast cancer, neoadjuvant chemotherapy, response rate

References

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