GIÁ TRỊ TIÊN ĐOÁN CÁC THANG ĐIỂM CHILD-PUGH, FIB-4 VÀ SAAG TRONG DỰ ĐOÁN GIÃN TĨNH MẠCH THỰC QUẢN Ở BỆNH NHÂN XƠ GAN CỔ CHƯỚNG

Abstract

Objective: To investigate the predictability of noninvasive indicators such as SAAG, Child-Pugh score and FIB-4 in detecting varicose esophageal varices in patients with ascites cirrhosis Patients and methods: A retrospective cross-sectional study was conducted on 75 patients with ascites cirrhosis admitted to the Department of Gastroenterology, Cho Ray hospital from 10/2019 to 06/2020. All patients underwent gastroscopy, SAAG, FIB-4, classified into Child-Pugh. Determination of cut-off point, sensitivity, specificity, area under the ROC curves of SAAG, FIB-4 and Child-Pugh score in patients with ascites with esophageal varices. Results: Among 75 patients, 74.7% were male, mean age was 55.57. and 92% patients had esophageal varices. SAAG and FIB-4 positively correlated with esophageal varices with r = 0.499 and 0/327, respectively. At cut-off point of 1.9 in patients with ascite cirrhosis, SAAG predicted esophageal varices with a sensitivity up to 88.37%, a specificity of 75.87%, and AUC of 0.982. Predictive value of FIB-4 at 3.16 had sensitivity of 79.09%, specificity of 68.75%. The Child-Pugh scale had a low predictive value. Conclusion: Combined SAAG and FIB-4 were non-invasive parameters with high sensitivity for predicting esophageal varices in ascites cirrhosis patients.