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Date Published: 02/06/2021
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DOI: https://doi.org/10.51298/vmj.v499i1-2.242
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Vol. 499 No. 1-2 (2021)
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Hồng Sơn, M., Bình An, N., & Ngọc Hà, L. (2021). CHARACTERISTIC IMAGING OF 99M TC-MAA SPECT/CT IN PRE-TREATMENT PLANNING OF 90Y RESIN MICROSPHERES IN HEPATOCELLULAR CARCINOMA. Vietnam Medical Journal, 499(1-2). https://doi.org/10.51298/vmj.v499i1-2.242

CHARACTERISTIC IMAGING OF 99M TC-MAA SPECT/CT IN PRE-TREATMENT PLANNING OF 90Y RESIN MICROSPHERES IN HEPATOCELLULAR CARCINOMA

Mai Hồng Sơn, Nguyễn Bình An, Lê Ngọc Hà

Main Article Content

Abstract

Background and aim: 99mTc-MAA SPECT/CT imaging is performed after radioembolization to re-evaluate the resin microsphere distribution and estimate the absorbed radiation dose of target tumor. However, role of 99mTc-MAA SPECT/CT simulation was not well established until now. The purpose of our study is to validate the utility of SPECT/CT compared to planar simulation in dosimetry. Material and method: Fifty - two consecutive HCC patients, intermediate and advanced stage who underwent 90Y resin microsphere transarterial embolization (TARE) were recruited in the study. Image characteristic and parameters: lung shunt fraction (LSF), tumor to-normal liver uptake ratio (TNr) and absorbed dose for target tumors were estimated on 99mTc-MAA SPECT/CT and planar. Results: The imaging characteristics including heterogeneity, necrosis and thrombosis uptake were better delineated on SPECT/CT imaging than planar. The agreement and correlation of TNr on SPECT/CT and planar were average (p<0,05. Dtumor on planar is lower than that on SPECT/CT with significant difference (P<0,05). Conclusions: 99mTc-MAA SPECT/CT is superior to planar in simulation before treatment 90Y resin microsphere in tumor delineantion and dosimetry.

Article Details

Keywords

99mTc-MAA SPECT, planar

References

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