CLINICAL AND SUBCLINICAL CHARACTERISTICS AND 18F-FDG CARDIAC PET/CT IMAGING IN PATIENTS WITH POST ACUTE MYOCARDIAL INFARCTION
Main Article Content
Abstract
Objectives: To investigate some characteristics of clinical, subclinical findings and 18F-FDG cardiac PET/CT imaging in patients with post acute myocardial infarction. Subjects and methods: This cross-sectional study included 45 patients with post acute myocardial infarction who were treated in Cardiology Institute, 108 military hospital from 2011 to 2015. Clinical, subclinical findings were collected and myocardial perfusion SPECT was undergone. 18F-FDG cardiac PET/CT was evaluated to assess myocardial viability and coronary angiography was done for patients who had indication. Results: mean age was 68,2±10,6, the proportion of the patients over 60 of age was 80%; the proportion of male was 91,1%. Risk factors of coronary artery disease as followed: hypertension (66,7%), smoking (35,6%). Left ventricular ejection fraction was 39,1±10,1%. Proportion of fixed defect without any reversible segment accouted for 68,9%. Percentage of severe defect and large defect in SPECT were 93,3%; 93,3% respectively. In PET/CT imaging, scar lesion took up 31,1%, hibernating myocardium was 68,9%, of which mixed lesion (hypernation combined with scar) were found in 46.67%,the unique hibernating was shown in 22.22%. Large size of scar lesion was 69,7%, large extent of hibernating took the highest percentage (45,2%). Conclusion: the result of SPECT imaging demonstrated that the patients with large and severe defect were seen the most common. In PET/CT imaging, the hibernating myocardium took up 45,2%.
Article Details
Keywords
myocardial viability, 18F-FDG PET/CT, myocardial perfusion SPECT/CT, acute myocardial infarction
References
2. A. Kositwattanarerk, C. Sritara and P. Sritara (2009) Correlation between myocardial perfusion imaging findings and cardiac events. J Med Assoc Thai, 92 (11), 1470-1475.
3. R. C. Hendel, D. S. Berman, M. F. Di Carli. et al (2009). ACCF/ASNC/ACR/AHA/ASE/SCCT/ SCMR/ SNM 2009 Appropriate Use Criteria for Cardiac Radionuclide Imaging: A Report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, the American Society of Nuclear Cardiology, the American College of Radiology, the American Heart Association, the American Society of Echocardiography, the Society of Cardiovascular Computed Tomography, the Society for Cardiovascular Magnetic Resonance, and the Society of Nuclear Medicine. J Am Coll Cardiol, 53 (23), 2201-2229.
4. J. A. Spertus, E. Peterson, J. S. Rumsfeld. et al (2006) The Prospective Registry Evaluating Myocardial Infarction: Events and Recovery (PREMIER)--evaluating the impact of myocardial infarction on patient outcomes. Am Heart J, 151 (3), 589-597.
5. Vũ Thị Phương Lan (2012) Nghiên cứu đặc điểm và giá trị tiên lượng cảu xạ hình tưới máu cơ tim ở bệnh nhân sau nhồi máu cơ tim, Luận án tiến sỹ y học, Viện Nghiên cứu Y Dược học lâm sàng 108.
6. M. J. Zellweger, G. Tabacek, A. W. Zutter. et al (2004) Evidence for left ventricular remodeling after percutaneous coronary intervention: effect of percutaneous coronary intervention on left ventricular ejection fraction and volumes. Int J Cardiol, 96 (2), 197-201.
7. Lê Ngọc Hà (2015) Nghiên cứu ứng dụng PET/CT sử dụng 18F- FDG trong bệnh nhồi máu cơ tim, ung thư hạch và ung thư đại – trực tràng. Chương trình KH & CN trọng điểm cấp nhà nước, BVTƯ QĐ 108.
8. P. J. Scanlon, D. P. Faxon, A. M. Audet. et al (1999) ACC/AHA guidelines for coronary angiography. A report of the American College of Cardiology/American Heart Association Task Force on practice guidelines (Committee on Coronary Angiography). Developed in collaboration with the Society for Cardiac Angiography and Interventions. J Am Coll Cardiol, 33 (6), 1756-1824.