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ASSESSMENT OF AXILLARY LYMPH NODE METASTASIS IN STAGE I-II BREAST CANCER (cT1-3N0M0) AT BREAST UNIT CHO RAY HOSPITAL
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Abstract
Background Breast cancer is the most common cancer in women in Vietnam as well as worldwide, the second leading cause of death after lung cancer. Evaluation of axillary lymph node metastases in breast cancer is essential in staging breast cancer and deciding on treatment. Axillary lymph node dissection is the standard local treatment of breast cancer in order to determine the exact stage of the patient. However, in the early stages, axillary lymph node dissection does not improve survival and increases complications. Objectives: This study compares the clinical and paraclinical preoperative axillary lymph node staging with postoperative histopathology and determines the accuracy of different staging methods. At the same time, give specific characteristics in the group of breast cancer patients stage I, II without lymph node metastasis. Method: Description of a retrospective series of patients diagnosed with stage I, II breast cancer with no axillary lymph node metastasis (cN0), treated with mastectomy or conservatively with lymph node dissection. armpit group I, group II at the Breast Unit of Cho Ray Hospital in 2021. Results: 46 patients with stage I, II (cN0) breast cancer underwent mastectomy or conservation with lymph node dissection. The majority of patients in the fifth decade of life (41-50 years of age) accounted for 42.5% of the study group. Regarding tumor size, the majority of T1 stage (1.1-2cm) accounted for 54.3%, 43.5% had T2 tumor and 2.2% had T3 tumor. Histology in 95.7% of tumors was invasive ductal carcinoma and 69.5% of tumors had high grade (II, III). The average number of dissected lymph nodes was 12.2 (from 7-30). The rate of axillary lymph node metastasis in this group of patients is about 21.7%. Conclusions: The study shows that: Axillary lymph node ultrasound is a minimally invasive and beneficial tool for preoperative lymph node staging and the rate of axillary lymph node metastasis in early breast cancer cT1-3N0M0 is 21.7%.
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Keywords
Axillary lymph node metastasis, cN0, breast cancer, mastectomy, preservation, lymph node dissection
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