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Date Published: 20/06/2022
Abstract Views: 173
Views PDF: 167
DOI: https://doi.org/10.51298/vmj.v514i1.2521
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Vol. 514 No. 1 (2022)
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Phương Chinh, D. ., Quốc Kính, N. ., Quang Minh, P. ., & Quang Thuỳ, L. . (2022). EVALUATE THE EFFECTS OF THE COMBINATION OF ETOMIDATE 2%-PHENYLEPHRINE 50mcg/ml VERSUS 2% ETOMIDATE ON CIRCULATION ALTERATIONS AND HYPERTENSION PREVENTION IN ADULT OPEN HEART SURGERY. Vietnam Medical Journal, 514(1). https://doi.org/10.51298/vmj.v514i1.2521

EVALUATE THE EFFECTS OF THE COMBINATION OF ETOMIDATE 2%-PHENYLEPHRINE 50mcg/ml VERSUS 2% ETOMIDATE ON CIRCULATION ALTERATIONS AND HYPERTENSION PREVENTION IN ADULT OPEN HEART SURGERY

Dương Phương Chinh1,, Nguyễn Quốc Kính1, Phạm Quang Minh2, Lưu Quang Thuỳ3
1 Vietnam-Germany Friendship Hospital
2 Hanoi Medical University
3 Bệnh viện Hữu nghị Việt Đức

Main Article Content

Abstract

Objectives: To evaluate the changes of some circulatory indices and the effect of preventing hypotension during induction stage of anesthesia with a mixture of 2% etomidate - phenylephrine 50mcg/ml compared with 2% etomidate in adult open heart surgery. Methods: Randomized controlled clinical trial on 60 patients with open heart surgery being divided into 2 groups: Group 1: inducing with etomidate 2% - 2ml NaCl 0.9%. Group 2: inducing with etomidate 2% - 2ml of phenylephrine 50mcg/ml. We evaluated the change of some circulatory indices (heart rate, CVP, blood pressure) and the proportion of patients with hypotension after induction stage of anesthesia between the 2 study groups. Results: There was no difference in some circulatory indices (heart rate, CVP, SBP, DPB, MBP) between the 2 study groups. The rate of hypotension was lower in the phenylephrine group (66.7% versus 90%). Conclusions: In open heart surgery in adults, performing induction of anesthesia with a mixture of etomidate-phenylephrine helps to prevent hypotension and does not affect the patient's circulatory status.

Article Details

Keywords

Etomidate, phenylephrine, hypotension in inducing stage of anesthesia, open heart surgery

References

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