RISK FACTORS ASSOCIATED WITH FREQUENTLY EXACERBATIONS IN ACUTE CHRONIC OBSTRUCTIVE PULMONARY DISEASE PATIENT HOSPITALIZED AT RESPIRATORY CENTRE OF BACH MAI HOSPITAL

Phùng Thị Thanh1,, Chu Thị Hạnh2, Trần Thị Nương1, Vũ Thanh Bình1
1 Thai Binh University of Medicine and Pharmacy
2 Tâm Anh Hospital

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Abstract

Objectives: To identify associations of some factors of frequent exacerbations in hospitalized patients with acute exacerbations of chronic obstructive pulmonary disease (COPD). Method: 118 COPD exacerbations inpatients treated at the respiratory center of Bach Mai hospital collected. Results: the group of patients had disease duration >5 years, CAT score ≥10 suffered from frequent exacerbations 4.9 times and 4.35 times more likely in comparison with other patients (p<0.05 and p<001, respectively). COPD patients with co-morbidities had double risk of frequent exacerbations compared with the group with non-co-morbidities, p < 0.05. Non-compliance with prescriptions had a risk of frequent exacerbations of hospitalization 3.3 times higher than that ò patients who adherence to prescriptions, p < 0.05. Using ICS was 3.2 times more likely to have frequent exacerbations of hospitalization than not using ICS, p < 0.05. There was no statistically significant relationship between smoking status and FEV1 index with frequent exacerbations of hospitalization. Conclusions: Disease duration > 5 years, CAT score ≥10, co-morbidities, non-adherence to prescription treatment, not use ICS are factors that associated with frequent exacerbations of COPD patients.

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References

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