RISK FACTORS ASSOCIATED WITH FREQUENTLY EXACERBATIONS IN ACUTE CHRONIC OBSTRUCTIVE PULMONARY DISEASE PATIENT HOSPITALIZED AT RESPIRATORY CENTRE OF BACH MAI HOSPITAL
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Abstract
Objectives: To identify associations of some factors of frequent exacerbations in hospitalized patients with acute exacerbations of chronic obstructive pulmonary disease (COPD). Method: 118 COPD exacerbations inpatients treated at the respiratory center of Bach Mai hospital collected. Results: the group of patients had disease duration >5 years, CAT score ≥10 suffered from frequent exacerbations 4.9 times and 4.35 times more likely in comparison with other patients (p<0.05 and p<001, respectively). COPD patients with co-morbidities had double risk of frequent exacerbations compared with the group with non-co-morbidities, p < 0.05. Non-compliance with prescriptions had a risk of frequent exacerbations of hospitalization 3.3 times higher than that ò patients who adherence to prescriptions, p < 0.05. Using ICS was 3.2 times more likely to have frequent exacerbations of hospitalization than not using ICS, p < 0.05. There was no statistically significant relationship between smoking status and FEV1 index with frequent exacerbations of hospitalization. Conclusions: Disease duration > 5 years, CAT score ≥10, co-morbidities, non-adherence to prescription treatment, not use ICS are factors that associated with frequent exacerbations of COPD patients.
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Keywords
Chronic obstructive pulmonary disease, COPD, exacerbation
References
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