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Date Published: 02/06/2021
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DOI: https://doi.org/10.51298/vmj.v499i1-2.258
Issue
Vol. 499 No. 1-2 (2021)
Section
Các bài báo
How to Cite
Thị Xuân, Đặng . (2021). EVALUATION OF FACTORS RELATED TO MORTALITY IN SEVERE SEPSIS PATIENTS. Vietnam Medical Journal, 499(1-2). https://doi.org/10.51298/vmj.v499i1-2.258

EVALUATION OF FACTORS RELATED TO MORTALITY IN SEVERE SEPSIS PATIENTS

Đặng Thị Xuân

Main Article Content

Abstract

Objective: Evaluation of factors related to acute renal failure and death in patients with severe sepsis. Subjects and Methods: A prospective observational study was conducted in patients with severe seppsis treated at ICU, Bach Mai hospital. Results: Severe sepsis increased the risk of AKI 2.1 times, p <0.05. The combination of AKI and severe sepsis is associated with a 61.6% mortality, increased the risk of death 4.7 timesas compared with AKI alone, p <0.001. Patients on dialysis have a mortality rate of up to 75%, and the risk of death is 21 times that of non-dialysis patients (OR 21; p <0.001). The group of patients with AKI after admission the highest death (80%), p <0.01; The risk of death was 8,0 times higher than of the group with mild upon admission, p <0.001. Conclusion: Severe infections increase the risk of AKI, severe infections with AKI increase the risk of death, especially in the severe group that requires hemodialysis and AKI after ICU admitted.

Article Details

Keywords

acute renal failure, severe sepsis, RIFLE

References

1. Bagshaw, S. M., et al. (2007). "Septic acute kidney injury in critically ill patients: clinical characteristics and outcomes". Clin J Am Soc Nephrol 2(3): 431-439.
2. Bellomo R., Ronco C., Kellum J A. (2004). “Acute renal failure – definition, outcome measures, animal models, fluid therapy and

information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group”. Critical Care, 8(20, 204-212.
3. Dellinger, R. P., et al. (2013). "Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012". Intensive Care Med 39(2): 165-228.
4. De Mendonca A., Vincent J.L. et al. (2000). "Acute renal failure in the ICU: risk factors and outcome evaluated by the SOFA score". Intensive Care Med 26(7): 915-921.
5. Metnitz, P. G., et al. (2002). "Effect of acute renal failure requiring renal replacement therapy on outcome in critically ill patients". Crit Care Med 30(9): 2051-2058.
6. Piccinni, P., et al. (2011). "Prospective multicenter study on epidemiology of acute kidney injury in the ICU: a critical care nephrology Italian collaborative effort (NEFROINT)". Minerva Anestesiol 77(11): 1072-1083.
7. Schrier R. W. and W. Wang (2004). "Acute renal failure and sepsis". N Engl J Med 351(2): 159-169.
8. Uchino, S., et al. (2005). "Acute renal failure in critically ill patients: a multinational, multicenter study". Jama 294(7): 813-818.
9. Singer M., et al. (2016). "The third international consensus definitions for sepsis and septic shock (sepsis-3)." JAMA 315(8): 801-810.