EVALUATION OF FACTORS RELATED TO MORTALITY IN SEVERE SEPSIS PATIENTS

Đặng Thị Xuân

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Abstract

Objective: Evaluation of factors related to acute renal failure and death in patients with severe sepsis. Subjects and Methods: A prospective observational study was conducted in patients with severe seppsis treated at ICU, Bach Mai hospital. Results: Severe sepsis increased the risk of AKI 2.1 times, p <0.05. The combination of AKI and severe sepsis is associated with a 61.6% mortality, increased the risk of death 4.7 timesas compared with AKI alone, p <0.001. Patients on dialysis have a mortality rate of up to 75%, and the risk of death is 21 times that of non-dialysis patients (OR 21; p <0.001). The group of patients with AKI after admission the highest death (80%), p <0.01; The risk of death was 8,0 times higher than of the group with mild upon admission, p <0.001. Conclusion: Severe infections increase the risk of AKI, severe infections with AKI increase the risk of death, especially in the severe group that requires hemodialysis and AKI after ICU admitted.

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References

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