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Date Published: 21/06/2022
Abstract Views: 299
Views PDF: 426
DOI: https://doi.org/10.51298/vmj.v514i2.2591
Issue
Vol. 514 No. 2 (2022)
Section
Các bài báo
How to Cite
Thị Xuân, Đặng ., & Trần Hưng, H. . (2022). CHARACTERISTICS OF ELEVATED OSMOL PRESSURE IN PATIENTS WITH ACUTE ETHANOL AND METHANOL POISONINGS. Vietnam Medical Journal, 514(2). https://doi.org/10.51298/vmj.v514i2.2591

CHARACTERISTICS OF ELEVATED OSMOL PRESSURE IN PATIENTS WITH ACUTE ETHANOL AND METHANOL POISONINGS

Đặng Thị Xuân1,, Hà Trần Hưng2
1 Poison Control Center, Bach Mai Hospital
2 Hanoi Medical University

Main Article Content

Abstract

Objective: to assess the characteristics of osmotic pressure increased in patients with acute ethanol and methanol poisonings. Subjects and methods: A prospective observational study on 121 acute ethanol and methanol poisoned patients with elevated osmol pressure treated at the Poison Control Center, Bach Mai Hospital was conducted from 7/2019 to 7/2020. Results: Ethanol and methanol poisonings caused an increase in osmotic pressure; 54.4% of ethanol poisonings and 72.3% of methanol poisonings had severe increases in OG. The higher the concentration of ethanol and methanol in blood, the higher osmalar gap (OG) (p<0.05). OG on admission in methanol poisoning patients was higher than ethanol poisoning (80.7 ± 40.53 vs 48.5 ± 29.36; p <0.05); the time OG returned to normal was longer than that of ethanol (23.5 ± 8.69 vs 11.2 ± 4.24; p <0.05). The blood osmolality gap decreased rapidly after admission, whereas the anion gap increases. Methanol poisonings were more severe, developed more complications than ethanol and had a higher rate of mortality (66.7% and 2.9%; p <0.05). Conclusion: The evaluation in elevated osmol pressure in patients with acute ethanol and methanol poisonings is essential for early prognosis of complications and having treatments for the patients

Article Details

Keywords

osmolar gap, ethanol and methanol

References

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