SO SÁNH TÁC DỤNG GIẢM ĐAU SAU PHẪU THUẬT VÙNG DƯỚI RỐN Ở BỆNH NHÂN NHI GIỮA TIÊM MORPHIN 3MCG/KG TUỶ SỐNG VỚI TIÊM MORPHIN 30MCG/KG KHOANG CÙNG

Abstract

Cotrol pain relief after pediatric surgery is very necessary, injectionmorphine into caudal space has been used for a long time but has potential side effects as well as technical difficulties. Intrathecal morphine injection has been introduced recently. We conducted a study to compare the pain relief effect and side effects of the two methods. Prospective study, randomized clinical trial was conducted at Hanoi Medical University Hospital. 75 pediatric patients, divided into 2 groups: Group 1 morphine 3mcg/kg intrathecal injection, Group 2 morphine 30 mcg/kg intrasacral space injection. Results: anthropometric index, type of surgery did not differ between the 2 groups. Group 1 having a pain relief time waslonger than group 2 (32.1 ±12.7 hoursto28.9 ± 10.7 hours), the difference was not statistically significant with p > 0.05. The FLACC scores of the two groups were lower than 3 scores at all the time point of the study, the need for additional analgesics was similar in the two groups. There was no patient with respiratory failure in 48 hours after surgery, group 1 had a higher rate of vomiting, nausea and itching than group 2, the difference was statistically significant with p < 0.05, the severity of these symptoms was mild. Conclusion: the spinal morphine injection group had similar analgesic effect as the sacral morphine injection group, there were no patients with respiratory failure. Side effects of group 1 were much more than group 2 but no required treament.