ĐÁNH GIÁ ĐỘ PHÙ HỢP GIỮA KẾT QUẢ MÔ BỆNH HỌC VÀ ĐẶC ĐIỂM NỘI SOI TRONG CHẨN ĐOÁN BỆNH VIÊM RUỘT MẠN TÍNH

Abstract

Introduction: Inflammatory bowel disease (IBD) is a disease with complicating pathophysiology and increasing prevalence worldwide. Diagnosis of IBD, especially in atypical cases, is based on the combination of clinical symptoms, endoscopic and histopathology results. Our study aimed to evaluate the level of agreement on the diagnosis of IBD between endoscopic and histopathology results. Methods: a descriptive retrospective study was conducted at Hanoi Medical University Hospital from February 2020 to October 2020 in patients who had endoscopy images suspected of ulcerative colistis (UC) or Crohn's diseases and had histopathology reports. The biopsy samples were examined independently by a histopathologist specialized in IBD in second round; the expert’s reports were compared with the first reports and the endoscopic results. Results: 46 patients met the selection criteria, the mean age was 44.23 (14.5), min-max was 19-74, the female/male ratio was 1.3. On endoscopy, 89.1% of patients were diagnosed with UC, only 5 patients were diagnosed with Crohn’s disease (10.9%). The levels of agreement between the endoscopy results and the first and the second histopathology reports were poor and moderate with κ coefficients of 0.265 and 0.491, respectively. The level of aggrement between the first and the second histopatholoy reports was moderate (κ = 0.487). Conclusion: The levels of aggrement between endoscopic results and histopathology results with and without expert opinion were low and medium (κ <0.6).