ĐÁNH GIÁ MỐI LIÊN QUAN GIỮA ĐẶC ĐIỂM TĨNH MẠCH TINH GIÃN TRÊN MÔ BỆNH HỌC VÀ CHỨC NĂNG TINH HOÀN Ở BỆNH NHÂN PHẪU THUẬT THẮT TĨNH MẠCH TINH GIÃN

Abstract

Varicocele is one of the most common abnormalities in men that affects testicular functions and may result in infertility. The structure of the varicosity vein changes based on the clinical progression. However, the influences of vein morphologies on testicular are not well-known in the literature. Thus, we conducted this study to investigate the relationship between changes in the vein’s structure and testicular function. Sixty-six men with grade III varicocele who were varicocelectomy at Hanoi Medical Univesity’s Hospital from 2014 to 2020. This study showed that most patients had vascular fibrosis with hypertrophy of vascular smooth muscle (43.9%) and vascular fibrosis (31.8%) in the histologic description. Vascular degeneration and hypertrophy of vascular smooth muscle were observed in 16.7% and 7.6%. Among parameters for testicular functions were tested, only total motile sperm count was found significant between groups with different histology. As a result of a post hoc analysis, patients with vascular fibrosis had a higher total motile sperm count than patients with vascular degeneration and vascular fibrosis with hypertrophy of vascular smooth muscle. These findings suggest an ability to use vascular histology as a potential predictor for varicocele treatment outcomes.