LIÊN QUAN, TƯƠNG QUAN GIỮA NHỊP SINH HỌC HUYẾT ÁP VỚI MICROALBUMIN NIỆU Ở BỆNH NHÂN ĐÁI THÁO ĐƯỜNG TÝP II CÓ TĂNG HUYẾT ÁP

Abstract

Aim: To determine the relationship and correlation between 24-hour ambulatory blood pressure parameters and microalbuminuria in patients with type II diabetes mellitus with hypertension. Subjects and methods: 31 patients with type II diabetes mellitus with hypertension, 19 males, 12 females, mean age 63.71 ±6.9 years, agreed to participate in the study. All patients had their clinical blood pressure measured with a mercury sphygmomanometer, then a 24-hour ambulatory blood pressure monitoring (ABPM) using a Suntech Oscar 2, USA machine with a measuring interval of every 30 minutes at day time from 6 AM to 10 PM and every 60 minutes at night time from 10 PM to 6 AM the next day and were tested the microalbuminuria on the same day with ABPM. Results: The mean albuminuria concentration in the nondipper patients group was significantly higher than in the dipper group; the patients group with 24-hour SBP overload ≥ 50% was significantly higher in the 24-hour SBP overload group <50%. There was a significant negative correlation between the albuminuria concentration and the dipper percentage for SBP with p < 0,05, r = -0,367; There was a significant negative correlation between the albuminuria concentration and the dipper percentage for DBP with p < 0,05, r = -0,399. Conclusion: There was a relationship, correlation between nocturnal reduction of blood pressure and blood pressure overload with microalbuminuria concentration in type II diabetic patients with hypertension.