VIÊM TUỴ CẤP DO RƯỢU VÀ DO TĂNG TRIGLYCERIDE MÁU: MỨC ĐỘ NẶNG VÀ KẾT CỤC LÂM SÀNG

Abstract

Objective: To investigate the severity and clinical outcomes of patients with alcohol-induced and hypertriglyceridemia-induced acute pancreatitis (AP). Methods: Descriptive cross-sectional study was conducted to compare the severity and outcomes between acute pancreatitis due to hypertriglyceridemia and alcohol. Patients aged 18 years or older, diagnosed with AP were included in this study. AP severity was assessed based on 2012 adjusted Atlanta scale, BISAP, CTSI and SIRS scale at the time of admission. Clinical outcomes included one or more organ failure complications, ICU admission and death. Results: The mean age of patients was 39.2 ± 9.7. Most of patients were men with the male/ female ratio of 3.5/1. There was no differences regarding a history of AP, diabetes and hypertension between the two groups. Patients with hypertriglyceridemia-induced AP were more severe than alcohol-induced AP patients (41.6% vs. 9.4%, p <0.001). SIRS and CTSI scores were statistically significant different between the two groups (p = 0.0058 and p = 0.0027). The rate of ICU admission and the length of hospitalization of hypertriglyceridemia-induced AP were higher than that in alcohol-induced AP patients (p = 0.038 and p = 0.042). Conclusion: Patients with hypertriglyceridemia-induced AP are more severe have longer hospital stay.