ANTIBIOGRAM AND TREATMENT RESULTS OF MENINGITIS PATIENTS TREATED IN NATIONAL HOSPITAL OF TROPICAL DISEASE

Thân Mạnh Hùng1,2,
1 University of Medicine and Pharmacy, Vietnam National University, Hanoi
2 National Hospital for Tropical Diseases

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Abstract

Objective: Describe the results of antibiogram and evaluate the treatment results of patients with meningitistreated in the emergency department - National hospital for tropical diseases. Subjects and methods: 42 patients were diagnosed with bacterial meningitis by methods: staining Gram, bacterial culture and polymerase chain, treated in the emergency department of national hospital for tropical diseases from 1/2013 to 12/2014. Descriptive and retrospective cross-sectional study. Results: Antibiogram: the causative agent is sensitive to ceftriaxone 83.9%, sensitive to ampicillin 93.5%, sensitive to meropnem 100%, sensitive to penicillin 96.6%, sensitive to cefepime 96, 4%. Treatment results: the mortality rate in patients with meningitis is 7.1%. Mean length of hospital stay was 19.11 days. The number of patients requiring mechanical ventilation accounted for 16.7%.

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References

1. Van de Beek D, De Gans J, Tunkel AR, et al. (2006). Community-acquired bacterial meningitis in adults. N Engl J Med. 354:44-53.
2. Conférence de consensus en thérapeutique anti-infectieuse du 19 novembre 2008 organisée par la Société de pathologie infectieuse de langue française (SPILF) : Prise en charge des méningites bactériennes aiguës communautaires (à l’exclusion du nouveau-né).
3. Nguyễn Thị Hoàng Mai, Ngô Thị Hoa, Trần Vũ Thiếu Nga, e al. (2008). Streptococcus suis meningitis in adults in Vietnam. Clinical Infectious Diseases. (46)5): 659-667.
4. WertheimH.F, Nguyễn Nguyên Huyền, Taylor W, et al. (2009). Streptococcus suis, an important cause of adult bacterial meningitis in northern Vietnam. PloS one, 4(6), e5973.
5. SakataH, SatoY, Nonoyama M, et al. (2010). Results of a multicenter survey of diagnosis and treatment for bacterial meningitis in Japan. Journal of infection and chemotherapy. 16(6), 396-406.