KHẢO SÁT SỰ BIẾN ĐỔI MỘT SỐ CHỈ SỐ ĐÔNG MÁU Ở BỆNH NHÂN SỐC NHIỄM KHUẨN

Abstract

Objectives: Evaluation of changes in some coagulation indices, SIC score and DIC score in dead and survivor group of septic shock patients. Materials and method: Prospective Descriptive Study on 60 septic shock patients treated in the Center of Emergency, Intensive Care Medicine and Clinical Toxicology - 103 Military Hospital - Vietnam Military Medical University. Results: Platelet count in the dead group was the highest value at the beginning of study (168±128.6 G/l), then tended to gradually decrease over time and reached the lowest value on the 7^th day (77±60.8 G/l). Platelet count at the 3^rd, 5^th and 7^th day of the dead group was lower than that of the survivor group, p<0.05. The SIC score at the 3^rd, 5^th, 7^th day and the DIC score on the 3^rd, 5^th day of the dead group higher than that of the survivor group, p<0.05. The SIC score had quite good and good predictive values for mortality on the 3^rd, 5^th, 7^th day with AUC of 0.726, 0.872, 0.827, respectively. The DIC score had weak and quite good predictive values for mortality on the 3^rd, 5^th day with AUC of 0.699 and 0.781, respectively. Conclusions: Platelet count in the dead group tended to decrease over time. Compared with the survivor group, the dead group had a lower platelet count, a higher SIC score on the 3^rd, 5^th, 7^th day and a higher DIC score on the 3^rd, 5^th day. The SIC score and DIC score had predictive values for mortality in septic shock patients.