INVESTIGATION ON GLUCOCORTICOID THERAPY FOR OUTPATIENTS USING GLUCOCORTICOID ORAL FOR 3 MONTHS OR MORE AT GIA DINH PEOPLE’S HOSPITAL

Đào Thị Diệu Ngân1, Huỳnh Thanh Sang2, Nguyễn Ngọc Khôi3, Nguyễn Như Hồ3,
1 Ninh Thuan General Hospital
2 Ho Chi Minh City University of Technology
3 University of Medicine and Pharmacy at Ho Chi Minh city

Main Article Content

Abstract

Objective: To report on adverse drug events (ADEs) in adults using glucocorticosteroids (GCs) for 3 months or more. Subjects and methods: A cross - sectional study was conducted on outpatients with people from 18 – 80 years old at Gia Dinh People’s Hospital between October 2020 and March 2021. Collected data for analysis included patient characteristics, pattern of systemic GCs uses, ADEs and associated factors. Results: We interviewed 157 patients about ADEs during their course of GC therapy. The median age of this group was 60 and most of them were female (64,1%). More than half of the patients (59,9%) reported using GCs for more than 12 months. Many patients with adrenal insufficiency were indicated GCs as replacement therapies (38,2%). Cushing’s syndrome was the most frequent adverse event (55,4%). Gender was associated with Cushing’s syndrome (OR = 2,72; 95% CI, 1,32 - 5,58) in patients with long – term use of GC. Conclusions: It is necessary to monitor closely outpatients prescribed with GCs in order to limit adverse events

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References

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