ULTRASOUND-GUIDED TRANSVERSUS ABDOMINIS PLANE BLOCK IN COMBINATION WITH PARACETAMOL AFTER CESAREAN DELIVERY

Trần Thị Sáu1, Nguyễn Văn Minh1,
1 Hue University of Medicine and Pharmacy Hospital

Main Article Content

Abstract

Background: Cesarean delivery (CD) is a commonly performed obstetric surgical procedure and causes moderate to severe postoperative pain, inadequate pain treatment causes many bad effects on pregnant women and babies. The objective of this study was to evaluate the effectiveness of ultrasound-guided transversus abdominis plane block (TAP block) in combination with paracetamol after CD. Materials and method: A total of 120 women after CD were allocated 1:1 to receive the TAP group or the control group protocol. The TAP group received TAP block and paracetamol. The control group received paracetamol and diclofenac. Pain intensity was assessed by the visual analogue scale (VAS) at 1, 2, 4, 6, 8, 12, 18, and 24 hours and the functional activity score (FAS) for the period from 1 - 8 h hours, from 8 - 16 h hours and from 16 - 24hours. Supplemental analgesic requirements were 5 mg of morphine intravenously when participants had a VAS score at rest ≥ 4 or a VAS score on movement ≥ 5. Results: The VAS score of the TAP-Para group was more effective than that of the control group in the peroid of 4 - 6 h hours, and the control group was more effective between 12 and 24 hours after CD. The FAS score from 1 - 8 hours of TAP-Para group was higher than that of the control group. The rate of supplemental analgesic requirements of the TAP-Para group was higher than that of the control group. Adverse effects of TAP-Para group accounted for a low rate. Conclusion: Ultrasound-guided TAP block combined with paracetamol was effective in the first 8 h hours after CD.

Article Details

References

1. Đàm Thị Phương Duy, Nguyễn Văn Minh, Trần Xuân Thịnh (2020), "Nghiên cứu hiệu quả của gây tê khoang cơ vuông thắt lưng bằng levobupivacain 0,25% dưới hướng dẫn siêu âm trong giảm đau đa mô thức sau phẫu thuật lấy thai", Y học cộng đồng, 7, tr. 1 - 81.
2. Abdallah F.W., Halpern S.H., Margarido C.B. (2012), "Transversus abdominis plane block for postoperative analgesia after Caesarean delivery performed under spinal anaesthesia? A systematic review and meta-analysis", British Journal of Anaesthesia, 109(5), pp. 679-87.
3. Carney J., Finnerty O., Rauf J., Bergin D., Laffey J.G., Mc Donnell J.G. (2011), "Studies on the spread of local anaesthetic solution in transversus abdominis plane blocks*", Anaesthesia, 66(11), pp. 1023-30.
4. Johns N., O'Neill S., Ventham N.T., Barron F., Brady R.R., Daniel T. (2012), "Clinical effectiveness of transversus abdominis plane (TAP) block in abdominal surgery: a systematic review and meta-analysis", Colorectal Dis. 14(0), pp. e635-42.
5. Macones G.A., Caughey A.B., Wood S.L., Wrench I.J., Huang J., Norman M., et al. (2019), "Guidelines for postoperative care in cesarean delivery: Enhanced Recovery After Surgery (ERAS) Society recommendations (part 3)", American Journal of Obstetrics & Gynecology, 221(3), pp. 247.e1-9.
6. Marzouk S.B., Bennasr L., Cherni I., Shili A., Touaibia M. (2016), "Ultrasound-guided bilateral transversus abdominis plane block versus spinal morphine for pain relief after caesarean section", Global Anesthesia and Perioperative Medicine, 2(2), pp. 162-5.
7. Meng X., Chen K., Yang C., Li H., Wang X. (2021), "The Clinical Efficacy and Safety of Enhanced Recovery After Surgery for Cesarean Section: A Systematic Review and Meta-Analysis of Randomized Controlled Trials and Observational Studies", Frontiers in Medicine, 8(1242).
8. Lirk P., Berde C.B. (2019), Local Anesthetics, Miller Anesthesia, ed. Ninth, Elsevier, 865-90.