NGHIÊN CỨU KẾT CỤC NỘI VIỆN TRÊN BỆNH NHÂN NHỒI MÁU CƠ TIM ST CHÊNH LÊN CÓ GÁNH NẶNG HUYẾT KHỐI LỚN ĐƯỢC HÚT HUYẾT KHỐI VÀ CAN THIỆP THÌ ĐẦU

Abstract

Background: Routine thrombus aspiration during primary PCI does not improve clinical outcomes. However, the outcomes of manual thrombus aspiration for patients undergoing primary PCI for acute STEMI with high thrombus burden is still unclear. Objective: Evaluate the in-hospital outcomes of using manual thrombus aspiration in STEMI patients under going primary PCI and showing high thrombus burden. Method: Interventon prospective study. Result: 147 STEMI patients with high thrombus burden in coronary angiography divides into thrombus aspiration and PCI (n = 71) or conventional PCI (n=76). The ST-segment resolution and TIMI myocardial perfusion grading (TMP = 3) were significant higher in the aspiration +PCI group compared with the conventional PCI group. In-hospital mortality rate was lower in the aspiration +PCI group compared with the conventional PCI group (10,5% versus 1,4%; p = 0,034). There was no significant differences in the incidence of stroke between two group. Conclusions: Aspiration thrombectomy in STEMI patient with high thrombus burden improved in-hospital mortality, ST-segment resolution and TIMI myocardial perfusion grading.