KHẢO SÁT NỒNG ĐỘ 1,5-ANHYDROGLUCITOL Ở BỆNH NHÂN ĐÁI THÁO ĐƯỜNG TÝP 2

Abstract

Background: 1,5-AG is a reflective of short-term blood glucose status that cannot be monitored with the HbA1c test. Objective: to investigate the change of 1,5-AG concentration in normal people and people with type 2 diabetes. Methods: Cross-sectional study design compared with the change of 1,5-Anhydroglucitol concentration between 2 groups of patients with diabetes (189) and without diabetes (150). Conducted at the Department of Biochemistry - Military Medical Hospital 175 - Ho Chi Minh City from February 2020 to July 2020. Results: 1.5-AG was significantly low in patients with type 2 diabetes, the average concentration was 9.7 ± 7.6 μg/ml, compared with the group of people without diabetes was 23.3 ± 8, 1 μg/ml, lower is statistically significant (p < 0.001). In the group of type 2 diabetes, there was no difference in the concentration of 1.5-AG by sex, the concentrations in men and women were: 9.1 ± 7.7 μg/ml, 10.4 ± 7.5, respectively. μg/ml (p = 0.184). The concentration of 1,5-AG in subjects without diabetes did not have a statistically significant difference when dividing by age group, at the age of < 40, 40 - 49, 50 - 59 years old, over 60 years old, respectively 17.9 ± 6.0 μg/ml, 22.7 ± 7.8 μg/ml, 23.3 ± 7.8μg/ml, 24.0±8.5μg/ml (p=0.111) ). Conclusion: Quantification of 1,5-AG has the ability to control blood sugar, especially in cases requiring short-term assessment.