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Date Published: 23/06/2022
Abstract Views: 247
Views PDF: 153
DOI: https://doi.org/10.51298/vmj.v515i2.2747
Issue
Vol. 515 No. 2 (2022)
Section
Các bài báo
How to Cite
Thất Kha, T. ., & Trung Vinh, H. . (2022). CORRELATION BETWEEN SERUM NT-ProBNP AND DOPPLER ECHOCARDIOGRAPHIC PARAMETERS IN BASEDOW’S PATIENTS WITH THYROTOXICOSIS. Vietnam Medical Journal, 515(2). https://doi.org/10.51298/vmj.v515i2.2747

CORRELATION BETWEEN SERUM NT-ProBNP AND DOPPLER ECHOCARDIOGRAPHIC PARAMETERS IN BASEDOW’S PATIENTS WITH THYROTOXICOSIS

Tôn Thất Kha1,, Hoàng Trung Vinh2
1 National Hospital of Endocrinology
2 Vietnam Military Medical University

Main Article Content

Abstract

Aims: Assessment correlate between serum NT-proBNP levels and doppler echocardiographic parameters in Basedow' patients with thyrotoxicosis. Subjects and methods: 258 Basedow' patients with thyrotoxicosis age 37,0 (27,0-52,0), female: 213 (83,6%); male 45 (17,4%). Serum NT-proBNP levels were measured by electroluminescence immunoassay (ECLIA) and doppler echocardiography performed in EPIQ 5G to determine some cardiac morphofunctional parameters. Results: NT-proBNP concentrations increased in patients with increased left atrial diameter, left ventricular end-diastolic diameter (Dd), right ventricular diameter, cardiac output (CO), ejection fraction (EF), systolic pulmonary artery pressure (sPAP), significantly related to the E/A ratio. The proportion of patients with NT-proBNP concentration in the range of 125-2000 pmol/l in subjects with increased left atrial and right ventricular diameter, CO >6 l/min, and sPAP at 41-65 mmHg was higher than in subjects who has respective indicators in normal range. Conclusion: The concentration of NT-proBNP was significantly associated with cardiac morphology and function on echocardiography in Basedow's patient with thyrotoxincosis.

Article Details

Keywords

Basedow’s disease, Hyperthyroidism, serum concentrations of NT-proBNP, echocardiography, cardiac dysfunction

References

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