EVALUATE THE EFFECTIVENESS OF TREATMENT OF ACNE SCARS BY FRACTIONAL CO2 LASER AND COMBINATION OF FRACTIONAL CO2 LASER WITH PLATELET-RICH PLASMA

Lê Thị Thu Hải1,, Nguyễn Thị Hồng Minh2, Nguyễn Thị Đông1
1 108 Military Central Hospital
2 Hanoi Central Odonto-Stomatology Hospital

Main Article Content

Abstract

Objective: To evaluate the efficacy of CO2 laser versus the combination of PRP and fractional CO2 laser in treatment of acne scar. Subject and method: A total of 32 cases with post-acne atrophic scars of moderate to severe grade were randomly allotted into Group A and Group B who were treated for three monthly sessions of fractional CO2 laser followed by intradermal PRP injection and fractional CO2 laser monotherapy, respectively. The treatment results were assessed after three months. Result: The mean scar score significantly reduced in both groups. The mean change in score was higher in subjects of Group B. The reduction in scar score was significantly higher in patients with rolling scars and boxcar scars and least in ice pick scars. Erythema, edema, pain, and hyperpigmentation were higher in Group A. Conclusion: Acne scar treatment by fractional CO2 laser is good results and safety. The combined use of fractional CO2 laser and platelet rich plasma achieved better results. It reduced the downtime of the fractional CO2 laser.

Article Details

References

1. Fabbrocini G, Annunziata MC, DArco, et al. Acne scars: patho‐ genesis, classification and treatment. Dermatol Res Pract.2010;2010:S93080
2. Manstein D., Herron G. S., Sink R. K., et al. (2004), Fractional photothermolysis: a new concept for cutaneous remodeling using microscopic patterns of thermal injury, Lasers Surg Med, 34(5), 426-38.
3. Leo, Michael S; Kumar, Alur S; Kirit, Raj; Konathan, Rajyalaxmi; Sivamani, Raja K (2015). Systematic review of the use of platelet-rich plasma in aesthetic dermatology. Journal of Cosmetic Dermatology, 14(4), 315–323.
4. Goodman GJ, Baron JA. Postacne scarring: a qualitative global scar‐ ring grading system. Dermatol Surg. 2006;32(12):1458‐1466.
5. Nguyễn Thị Kim Cúc và Phạm Thị Lan (2017), "Hiệu quả điều trị sẹo lõm sau trứng cá bằng Radiofrequency (RF) vi điểm xâm nhập", Tạp chí Nghiên cứu Y học, 107(2), tr. 150-157.
6. Galal O, Tawfik AA, Gohdan N, Soliman M. Fractional CO2 laser versus combined platelet‐ rich plasma and fractional CO2 laser in treatment of acne scars: Image analysis system evaluation. J Cosmet Dermatol. 2019;00:1–7.
7. Arsiwala NZ, Inamadar AC, Adya KA. A comparative study to assess the efficacy of fractional carbon dioxide laser and combination of fractional carbon dioxide laser with topical autologous platelet-rich plasma in post-acne atrophic scars. J Cutan Aesthet Surg 2020;13:11-7.
8. Nguyễn Thế Vỹ, Nguyễn Quốc Hưng, Đàm Thúy Hồng (2017), Đánh giá hiệu quả điều trị sẹo lõm do trứng cá Fractional CO2 tại Bệnh viện Da liễu Hà Nội, Tạp chí Y dược lâm sàng 108, Hội nghị Khoa học Ứng dụng Laser trong Y học Toàn quốc lần thứ 4, 102-106.