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Date Published: 23/06/2022
Abstract Views: 226
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DOI: https://doi.org/10.51298/vmj.v515i2.2756
Issue
Vol. 515 No. 2 (2022)
Section
Các bài báo
How to Cite
Ngân Hà, N. ., Minh Phú, N. ., Phú Trang Hưng, N. ., & Thị Hải Yến, N. . (2022). RESEARCH ON THE RETINAL VASCULAR LESIONS IN DIABETIC RETINOPATHY. Vietnam Medical Journal, 515(2). https://doi.org/10.51298/vmj.v515i2.2756

RESEARCH ON THE RETINAL VASCULAR LESIONS IN DIABETIC RETINOPATHY

Nguyễn Ngân Hà1,2,3,, Nguyễn Minh Phú2, Nguyễn Phú Trang Hưng1, Nguyễn Thị Hải Yến1
1 Hanoi Medical University
2 Central Eye Hospital
3 Boston University Medical Campus (BUMC)

Main Article Content

Abstract

Purpose: Evaluate the retinal vascular lesions associated with diabetes. Methods: This study included two groups: Normal mice and streptozotocin induced diabetic mice. Retinal trypsin digest was performed to assess acellular capillarries and pericyte loss. Moreover, retinal vascular permeability was analyzed following FITC-dextran injection in retinal whole mounts. Results: The number of acellular capillaries and pericyte loss increased significantly in diabetic mice group. Furthermore, diabetic mice also showed an increase in retinal vascular permeability. Conclusion: HG promote retinal vascular cell loss and excess permeability in diabetic retinopathy.

Article Details

Keywords

Diabetic retinopathy, retinal vascular cell, retinal vascular permeability

References

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