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Date Published: 23/06/2022
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DOI: https://doi.org/10.51298/vmj.v515i2.2760
Issue
Vol. 515 No. 2 (2022)
Section
Các bài báo
How to Cite
Kim Thư, N. ., & Viết Nghĩa, L. . (2022). EVALUATION OF TREATMENT RESULTS IN BURKHOLDERIA PSEUDOMALLEI INFECTED PATIENTS AT THE NATIONAL HOSPITAL FOR TROPICAL DISEASES FROM 2016-2021. Vietnam Medical Journal, 515(2). https://doi.org/10.51298/vmj.v515i2.2760

EVALUATION OF TREATMENT RESULTS IN BURKHOLDERIA PSEUDOMALLEI INFECTED PATIENTS AT THE NATIONAL HOSPITAL FOR TROPICAL DISEASES FROM 2016-2021

Nguyễn Kim Thư1,2,, Lê Viết Nghĩa2
1 National Hospital for Tropical Diseases
2 Hanoi Medical University

Main Article Content

Abstract

Objectives: evaluation of a treatment outcome of patients infected with Burkholderia pseudomallei at the National Hospital for Tropical Diseases. Methods: cross-sectional study was conducted on 79 patients with confirmed of Burkholderia pseudomallei infection, between 2016 and 2021, at National Hospital of Tropical Diseases. Results and conclusions: Antibiotic susceptibility rate of 75 Burkholderia pseudomallei isolates: imipenem 93,2%; meropenem 96,3%; ceftazidim 93,3%; Amo + A.clavulanic 88,4%; TMP-SMX 82,2%; doxycyclin 100%; Tetracyclin 76,2%. Antibiotic resistance rate of 75 Burkholderia pseudomallei isolates: imipenem 2,7%; meropenem 3,7%; ceftazidim 1,3%; Amo + A.clavulanic 9,3%; TMP-SMX 16,4%; tetracyclin 14,3%. TMP-SMX did not reduce mortality rate and fever time when combined with intravenous antibiotics. The overall mortality rate was 11.4%. The mean hospital stay period was 26.72 ± 16.20 days. The fever time after treatment was mainly less than 7 days, accounting for 53.4%.

Article Details

Keywords

Melioidosis, Burkholderia pseudomallei

References

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