ASSESSMENT OF CONTINOUS VENO-VENOUS HEMOFILTRATION EFFICACITY IN SEPTIC SHOCK INDUCED MULTIORGAN FAILURE SYNDROME IN ICU NGHE AN GENERAL FRIENDSHIP HOSPITAL

Nguyễn Đức Phúc1,, Trần Phương2, Trịnh Xuân Nam2, Trần Văn Thảnh2
1 Bệnh viện Hữu nghị đa khoa Nghệ An
2 Nghe An Friendship General Hospital

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Abstract

Objective: of clinical and subclinical efficacy of continuous hemodialysis in the treatment of multi-organ failure due to septic shock. Methods: Prospective study on 32 patients with MOFS from septic shock  were treated CVVH  at the ICU of Nghe an friendship hospital from 01/2021  to 09/2021. Results: 32 patients, 23 males, 09 females, the mean age 51.6 ± 13.6, septic shock with respiratory tract 53%. Severity before dialysis, APACHE II score 20.5 ± 4.2, SOFA score 10.6 ± 3.5, organ failure 2.7 ± 1.2. There were 18 (56%) patients out of shock, 17 (53%) died. The survival rate among patients who started CVVH  within 24 h after onset of multiple organ failure was significantly higher than in the group who started CVVH  later (61.1% vs 21.4%, p). <0.05). Conclusion: CVVH  is effective in treating multi-organ failure due to septic shock, so an early CVVH  strategy should be introduced for septic shock patients with multi-organ failure.

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References

1. Singer M., Deutschman C.S., Seymour C.W., al e. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016;315(8):801-810.
2. Angus D.C, Van der Poll T. Severe Sepsis and Septic Shock. N Engl J Med. 2013;369(9):840-851.
3. Cecconi M EL, Levy M RA. Sep-sis and septic shock. Lancet. 2018;392(10141):75-87.
4. Vincent J.L., Moreno R., Takala J., al e. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med. 1996; 22(7):707-710.
5. Hoàng Văn Quang (2009), “Nghiên cứu hiệu quả lọc máu liên tục thể tích cao điều trị suy đa tạng trong sốc nhiễm khuẩn”, Tạp chí Y học thực hành, Số 1: 25-29.
6. Nguyễn Xuân Nam (2010),” Đánh giá hiệu quả của lọc máu liên tục trong suy đa tạng do sốc nhiếm khuẩn” Tạp chí Y học Việt nam, Tập 369, số 2: 18-21
7. Lê Thị Diễm Tuyết - Trần Minh Tuấn (2007), “Đánh giá tác dụng của lọc máu liên tục trong điều trị BN suy đa tạng”, Báo cáo chuyên đề hội nghị Hồi sức toàn quốc 4/2007, 39-43.
8. Ronco C , Bellomo R , Ricci Z (2012), “Important of increased ulfiltration volume and impact on mortality: sepsis and cytokine story and the role for CVVH”, EDTNA/ERCA Dialysis Technology Journal Club, (suppl 2): 13-19