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Date Published: 23/06/2022
Abstract Views: 144
Views PDF: 125
DOI: https://doi.org/10.51298/vmj.v515i2.2788
Issue
Vol. 515 No. 2 (2022)
Section
Các bài báo
How to Cite
Việt Hùng, Đinh ., Đình Khanh, N. ., Xuân Tĩnh, Đỗ ., Tiến Trường, Đặng, & Thị Ngọc Trường, T. . (2022). RESEARCH ON MORPHOLOGICAL CHARACTERISTICS OF FRONTAL LOBE ON MRI IN PATIENTS WITH ALCOHOL USE DISORDER. Vietnam Medical Journal, 515(2). https://doi.org/10.51298/vmj.v515i2.2788

RESEARCH ON MORPHOLOGICAL CHARACTERISTICS OF FRONTAL LOBE ON MRI IN PATIENTS WITH ALCOHOL USE DISORDER

Đinh Việt Hùng1,, Nguyễn Đình Khanh1, Đỗ Xuân Tĩnh1, Đặng Tiến Trường2, Trần Thị Ngọc Trường1
1 Military Hospital 103
2 Vietnam Military Medical University

Main Article Content

Abstract

Objectives: Morphological characteristics of frontal lobe on MRI in patients with alcohol use disorder.  Subject and methods: Descriptive research, cross-section in 30 inpatients with alcohol use disorder at the Psychiatric Department, 103 Military Hospital from April 2021 to March 2022, and 21 healthy controls. Results: The total gray matter volume of the frontal lobe in the group of patients decreased compared to the control group (91,83 ± 1,35cm3 versus 97,29 ± 1,62cm3, with p<0,05). The volume of the right orbital gyrus gray matter and the left precentral gyrus volume in the patient group decreased compared to the control group (5,96 ± 0,1cm3 and 4,85 ± 0,11cm3 versus 6,24 ± 0,13cm3 and 5,20 ± 0,13cm3, with p<0,05). The thickness of superior frontal gyrus gray matter in the patient group decreased compared to the control group (2,55 ± 0,04 mm versus 2,68 ± 0,03 mm, with p<0,05). The volume of the superior frontal gyrus white matter, the medial frontal gyrus, the inferior frontal gyrus, and the precentral gyrus in the patient group decreased compared to the control group (34,27 ± 0,75 cm3; 37,16 ± 0,69 cm3; 14,01 ± 0,32 cm3 and 26,35 ± 0,48 cm3 versus 37,54 ± 0,90 cm3; 40,54 ± 0,83 cm3; 15,68 ± 0,38 cm3 and 30,08 ± 0,57 cm3, with p<0,05). Conclusion: The total gray matter volume of the frontal lobe, white matter volume of superior frontal gyrus, medial frontal gyrus, inferior frontal gyrus, and precentral gyrus decreased in the patient group compared to the control group.

Article Details

Keywords

Alcohol use disorder, Frontal lobes, Gray matter, White matter

References

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