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Date Published: 23/06/2022
Abstract Views: 871
Views PDF: 373
DOI: https://doi.org/10.51298/vmj.v515i2.2792
Issue
Vol. 515 No. 2 (2022)
Section
Các bài báo
How to Cite
Thị Mai Anh, N. ., & Thị Thu Trang, N. . (2022). PREPARATION AND EVALUATION GEL IN SITU FILM TO COVER THE SKIN RHAGADES. Vietnam Medical Journal, 515(2). https://doi.org/10.51298/vmj.v515i2.2792

PREPARATION AND EVALUATION GEL IN SITU FILM TO COVER THE SKIN RHAGADES

Nguyễn Thị Mai Anh1,, Ngô Thị Thu Trang1
1 Hanoi University of Pharmacy

Main Article Content

Abstract

Gel in situ films are liquid preparations that are applied directly to the skin and form a thin film locally after application. In this study, gel in situ film was prepared from Eudragit RS 100, Eudragit  RL 100 and hydroxypropyl methyl cellulose E6 with volatile solvents and plasticizer triethyl citrate. The liquid gel was easy to use, it created a film on the skin quickly within 2 minutes. The formed film had good mechanical strength and high elasticity. The film on the skin could be well waterproof within 3 hours and had good adhesion on the skin in water for 3 hours. The product was suitable for covering skin rhagades in all shapes and sizes, which created favorable condition for wound healing and ensured normal labor activities. The were no signs of allergic reaction on the rabbit’s skin after 72 hours of applying the hydrogel.

Article Details

Keywords

gel in situ film, rhagades

References

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