CÁC YẾU TỐ NGUY CƠ CỦA BỆNH HUYẾT KHỐI TĨNH MẠCH NÃO

Abstract

Objective: To describe risk factors of cerebral venous thrombosis. Subjects and methods: A prospective, descriptive study of 38 patients with cerebral venous thrombosis treated at the Department of Neurology, Bach Mai Hospital from March 2020 to June 2021. Results: The mean age was 42.4 ± 14.8, the male/female ratio was 1.2:1. The rate of lack of risk factors for primary hypercoagulability PC, PS, ATIII was 39.5%, of which protein S deficiency was the most common (21.1%), protein C and ATIII deficiency was 18, 4% and 10.5%. In women, oral contraceptives, childbirth, after miscarriage or abortion are important risk factors for cerebral venous thrombosis in which oral contraceptive use was the major risk factor (44.2%). The risk factors for secondary hypercoagulation related to antibodies were found with a low rate, of which antiphospholipids were the highest (5.3%), antinuclear antibodies ANA (2.6%), anti dsDNA (2.6%), anti cardiolipin (2.6%). Some of the risk factors we also encountered in the study group of patients included: Diabetes mellitus (5.3%), basedow (5.3%), polycythemia vera (5.3%). Conclutions: The rate of lack of risk factors for primary hypercoagulability PC, PS, ATIII was 39.5%, of which protein S deficiency was the most common (21.1%). In women, oral contraceptives was the major risk factor (44.2%). The risk factors for secondary hypercoagulation related to antibodies were found with a low rate were antiphospholipids (5.3%), antinuclear antibodies ANA (2.6%), anti dsDNA (2.6%), anti cardiolipin (2.6%).