RESEARCH CHARACTERISTICS OF POWER DOPPLER ULTRASOUND OF THE WIRST IN PATIENT WITH RHEUMATOID ARTHRITIS AT NGHE AN FRIENDSHIP GENERAL HOSPITAL

Nguyễn Thị Thúy1,
1 Nghe An Friendship General Hospital

Main Article Content

Abstract

Evaluation of disease activity plays an important role in the treatment and monitoring of patients with rheumatoid arthritis. Objectives:To describe the characteristics of energy Doppler ultrasound of wrist joints in patients with rheumatoid arthritis. Determining some factors related to the image of wrist joint damage on energy Doppler ultrasound with some clinical and subclinical characteristics of the disease. Subjects and methods of study: A cross-sectional description was performed on 103 rheumatoid arthritis patients at the musculoskeletal department of Nghe An General Hospital. Results: Wrist vascular proliferation on PDUS level Grade 1 (mild proliferation) accounted for 58.25%, level 2 (moderate proliferation) was 24.27% and 7.70% at level 3 (strong proliferation);. The degree of angiogenesis according to the semi-quantitative scale on energy Doppler ultrasound of the wrist joints in rheumatoid arthritis patients has a significant relationship with factors reflecting the clinical and laboratory activity of the disease. is the number of swollen joints, the number of painful joints, the overall VAS, the CRP concentration and the commonly used disease activity index, which is DAS28-CRP. Conclusion:Power Doppler ultrasound of the wrist joint can be used as a method to measure rheumatoid arthritis activity level.

Article Details

References

1. Szkudlarek, M., et al., Power Doppler ultrasonography for assessment of synovitis in the metacarpophalangeal joints of patients with rheumatoid arthritis: a comparison with dynamic magnetic resonance imaging. Arthritis Rheum, 2001. 44(9): p. 2018-23.
2. McInnes, I.B. and G. Schett, The pathogenesis of rheumatoid arthritis. N Engl J Med, 2011. 365(23): p. 2205-19.
3. Newsome, G., Guidelines for the management of rheumatoid arthritis: 2002 update. J Am Acad Nurse Pract, 2002. 14(10): p. 432-7.
4. Rees, J.D., et al., A comparison of clinical vs ultrasound determined synovitis in rheumatoid arthritis utilizing gray-scale, power Doppler and the intravenous microbubble contrast agent 'Sono-Vue'. Rheumatology (Oxford), 2007. 46(3): p. 454-9.
5. Vreju, F., et al., Power Doppler sonography, a non-invasive method of assessment of the synovial inflammation in patients with early rheumatoid arthritis. Rom J Morphol Embryol, 2011. 52(2): p. 637-43.
6. Backhaus, M., et al., [Technique and diagnostic value of musculoskeletal ultrasonography in rheumatology. Part 6: ultrasonography of the wrist/hand]. Z Rheumatol, 2002. 61(6): p. 674-87.
7. Smolen, J.S., et al., EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update. Ann Rheum Dis, 2014. 73(3): p. 492-509.
8. Ellegaard, K., et al., Ultrasound colour Doppler measurements in a single joint as measure of disease activity in patients with rheumatoid arthritis--assessment of concurrent validity. Rheumatology (Oxford), 2009. 48(3): p. 254-7.
9. Spârchez, M., D. Fodor, and N. Miu, The role of Power Doppler ultrasonography in comparison with biological markers in the evaluation of disease activity in Juvenile Idiopathic Arthritis. Med Ultrason, 2010. 12(2): p. 97-103.