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Date Published: 23/06/2022
Abstract Views: 1234
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DOI: https://doi.org/10.51298/vmj.v515i2.2798
Issue
Vol. 515 No. 2 (2022)
Section
Các bài báo
How to Cite
Thị Ngọc Hà, N. ., Thị Thu Hằng, V. ., Thị Thu Hương, B. ., & Thị Thu Hương, L. . (2022). RESEARCH ON CHANGES OF IRON AND SERUM FERRITIN IN CIRRHOTIC PATIENTS AT THAI NGUYEN CENTRAL HOSPITAL. Vietnam Medical Journal, 515(2). https://doi.org/10.51298/vmj.v515i2.2798

RESEARCH ON CHANGES OF IRON AND SERUM FERRITIN IN CIRRHOTIC PATIENTS AT THAI NGUYEN CENTRAL HOSPITAL

Nguyễn Thị Ngọc Hà1,, Vũ Thị Thu Hằng1, Bùi Thị Thu Hương1, Lâm Thị Thu Hương1
1 Thai Nguyen University of Medicine and Pharmacy

Main Article Content

Abstract

Objectives: To determine the changes in serum iron and ferritin in patients with cirrhosis and to analyze the relationship between the changes in iron and serum ferritin with the clinical of cirrhosis. Subjects & methods: 94 cirrhotic patients treated at Thai Nguyen Central Hospital were divided into 3 groups of cirrhosis caused by hepatitis B virus, alcoholic cirrhosis, alcoholic cirrhosis and HBV infection. The patient was examined and had hematological and biochemical tests (iron, ferritin, albumin, prothrombin), HCV, HBV. Research results: Serum ferritin levels in all 3 groups caused by hepatitis virus, alcohol abuse and the group combines the above 2 reasons were mainly at normal and high levels, almost no ferritin at low levels (p>0.05). The mean serum iron concentration was high in the group of patients with hepatitis due to combined causes (p<0.05). Serum iron and ferrin concentrations were increased in Child Pugh B and C stages, especially in the cirrhosis group of combined causes. There was no association between serum iron, ferritin and anemia. Patients with high ferritin concentration were mainly seen in the group with decreased albumin. Decrease in serum iron is not associated with decreased albumin. Decreased prothrombin was associated with decreased serum iron, increased serum ferritin (p>0.05). Conclusion: Most patients with cirrhosis have elevated serum iron and ferritin

Article Details

Keywords

Serum iron, serum ferritin, cirrhosis

References

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