CORRELATION BETWEEN LEFT ATRIAL STIFFNESS WITH LEFT ATRIAL FUNCTION AND NT-PROBNP IN PATIENTS WITH HEART FAILURE WITH PRESERVED EJECTION FRACTION

Đỗ Văn Chiến1, Lương Hải Đăng1,, Mạc Thanh Tùng1
1 108 Military Central Hospital

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Abstract

Objective: To investigate the relationship between echocardiographic left atrial stiffness and left atrial echocardiographic indices and serum NT-proBNP levels in heart failure patients with preserved ejection fraction. Subjects and methods: 47 subjects diagnosed HFpEF treated at 108 Military Central Hospital from June 2020 to June 2021. All patients were tested for NT-proBNP levels and echocardiography assessed left atrial stiffness according to the LASt=E/e'/LASr equation. Results: the average age was 67.04±12.6 years old, male accounted for a high proportion of 78.7%. Left atrial stiffness (LASt) has a strong negative correlation with LA reservoir function (LASr) with r=-0.603; p<0.001, moderate for LA conduit function (LAScd) with r=0,354; p=0.017 and LA contractility (LASct) with r=0.492; p=0.001. LASt also has a moderate positive correlation with serum NT-proBPN levels with r=0,408; p=0.005. Conclusion: Left atrial stiffness assessed by tissue Doppler echocardiography and speckle tracking is correlated with left atrial functions such as reservoir, conduit, contractility and serum NT-proBNP levels. .

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References

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