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PORTAL HYPERTENSIVE GASTROPATHY OF CHRONIC LIVER DISEASES IN CHILDREN
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Abstract
Portal hypertension (PH) in children is caused by many causes. In patients with chronic liver disease, PH is one of the poor prognostic factor. Upper gastrointestinal endoscopy is not only considered as the gold standard to diagnosis PH, classify grade gastroesophageal varices, detect other lesions but also assess the risk of gastrointestinal bleeding, use interventional and prophylactic measures. This is a cross-sectional study on 79 chronic liver disease who were diagnosed PH by endoscopy. The study was conducted at the National Children's Hospital from July 2019 to October 2020. The results of the study showed 58.2% of chronic liver disease patients in the age 1-5 years had PH. Common clinical symptoms include splenomegaly 98.7%, hepatomegaly 44.3%, thrombocytopenia 73.4%; anemia 60.8%, decrease in white blood cell count 15.2% and neutropenia 12.7% and abnormal liver function tests. The esophageal varices on endoscopic examination at the time of diagnosis was mainly at grade I (26.5%) and grade II (46.8%), the rate of varices grade III (15.6%), grade IV (10 ,2%). Other combined lesions include gastric mucosal inflammation (92.4%), gastric varices (26.6%), duodenal ulcer 10.1%. It is necessary to detect and diagnose ASCVD early in patients with chronic liver disease in order to reduce the rate of complications and the risk of death. Key words: Portal hypertension, esophageal varices, chronic liver disease
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